Electrophysiological analysis of synaptic transmission / Nicholas Graziane, Neuroscience Department, University of Pittsburg, Pittsburg, PA, USA, Yan Dong, Neuroscience Department, University of Pittsburg, Pittsburgh, PA, USA
Extracellular and intracellular recordings -- Electrical theory -- Amplifiers -- Salt environment -- Patch pipettes (micropipettes) -- Spatiotemporal effects of synaptic current -- Perforated patch -- Isolation of synaptic current -- Fast and slow synaptic currents -- Measuring kinetics of synaptic current -- Measuring presynaptic release probability -- Long-term measurements -- Measuring reversal potentials -- Amplitude -- Pre vs. post synaptic effect -- Run-up and run-down -- Kinetics of synaptic current -- Measurement of a single synapse -- Measurement of silent synapses -- Dendritic patch -- Electrophysiological and visual tags -- Extracellular recordings
Summary
Electrophysiology is one of the finest approaches capable of detecting and analyzing electrical events in the brain. However, like all other experimental approaches, it has its limitations. This book was created to serve as a guide for those endeavoring to understand the function of electrophysiology and its underlying components: neurons, neural systems, and the brain. It introduces and highlights important topics in the field of electrophysiology, while also extending these topics to practical electrophysiological approaches through the perspective of the two authors. This book is ideal for graduate students or junior postdoctoral fellows interested in starting a journey in synaptic neuroscience
Bibliography
Includes bibliographical references and index
Notes
Online resource; title from PDF title page (SpringerLink, viewed December 21, 2015)
