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Book Cover
E-book
Author Brignole, Michele.

Title Syncope : an evidence-based approach / Michele Brignole, David G. Benditt ; foreword by Richard Sutton
Published London ; New York : Springer, ©2011

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Description 1 online resource (xvii, 344 pages) : illustrations (chiefly color)
Contents SECTION ONE A -- Current evidence-based knowledge: Classification, Pathophysiology and Social / Economic Impact -- Chapter 1. Syncope: definition, terminology, and classification -- 1.1 Definition -- 1.1.1 Loss of consciousness -- 1.1.2 Onset is relatively rapid -- 1.1.3. Recovery is spontaneous, complete and usually prompt -- 1.1.4. Underlying mechanism is transient global cerebral hypoperfusion -- 1.2. Terminology -- 1.3. Classification -- 1.3.1 Neurally-Mediated Reflex Syncope -- 1.3.2 Orthostatic (Postural) Syncope -- 1.3.3 Cardiac (Cardiovascular) Syncope -- 1.4. Conclusion -- Chapter 2. Pathophysiology of syncope -- 2.1 Maintenance of Adequate Cerebral Blood Flow -- 2.1.1 Autonomic Neural Control -- 2.1.2 Cerebrovascular Autoregulation -- 2.2 Failure to Maintain Cerebrovascular Perfusion -- 2.2.1 Neurally-mediated cerebral hypoperfusion -- 2.2.2 Non-neurally-mediated causes of hypotension -- 2.3 Clinical perspectives -- Chapter 3. Epidemiology of syncope (fainting) -- 3.1 Prevalence and Incidence -- 3.1.1 Community-based estimates -- 3.1.2 Selected population estimates -- 3.2 Syncope recurrences -- 3.3 Mortality Concerns -- 3.4 Unresolved Prognostic Issues -- 3.5 Clinical Perspectives -- Chapter 4 Syncope burden: economic impact of syncope on healthcare resources and personal well-being -- 4.1 Cost of TLOC/Syncope Care -- 4.1.1 Current Status -- 4.1.2 Opportunity for Reducing Cost -- 4.2 Quality of life -- 4.3 Clinical perspectives -- SECTION ONE B -- Current evidence-based knowledge: Structured Diagnostic Strategy -- Chapter 5. The initial evaluation of T-LOC: diagnostic strategy based on the initial findings -- 5.1 The Initial evaluation -- 5.1.1 History and physical examination -- 5.1.2 Baseline electrocardiogram -- 5.1.3 Additional tests -- 5.2 The 3 main question to be addressed at initial evaluation -- 5.2.1 Is loss of consciousness attributable to syncope or not? -- 5.2.2. Is heart disease present or absent? -- 5.2.3. Is there features in the history that suggest the diagnosis? -- 5.3 The diagnostic strategy based on the initial evaluation -- 5.3.1 Certain diagnosis -- 5.3.2 Uncertain diagnosis -- 5.4 Diagnostic yield of the initial evaluation -- 5.5 Clinical perspectives -- Chapter 6. T-LOC Risk stratification -- 6.1 Introduction -- 6.2 Assessing the risk -- 6.2.1 Risk of death and life-threatening events -- 6.2.2 Risk of syncope recurrence -- 6.3 Management according to risk stratification -- 6.4 Clinical perspectives: in-hospital versus out-patient evaluation in specialized facilities -- Chapter 7. Indications for and interpretation of laboratory diagnostic tests -- 7.1 Introduction -- 7.2 Carotid sinus massage -- 7.2.1 Indications -- 7.2.2 Interpretation of results -- 7.3 Orthostatic challenge (Active Standing Test and Tilt-table Testing) -- 7.3.1 Active Standing Test -- 7.3.2 Tilt-table testing -- 7.4 ATP (Adenosine) test -- 7.4.1 Indications -- 7.4.2 Interpretation of results -- 7.5 Electrophysiological study -- 7.5.1 Suspected sinus node disease (SND) -- 7.5.2 Bundle Branch Block -- 7.5.3 Suspected supraventricular tachycardia -- 7.5.4 Suspected ventricular tachycardia -- 7.5.5 Indications -- 7.5.6 Interpretation of results -- 7.6.1 Indications -- 7.6.2 Interpretation of results -- 7.7 Other tests -- 7.8 Diagnostic yield of laboratory tests in patients with uncertain syncope -- 7.9 Clinical perspectives -- Chapter 8. Prolonged Ambulatory ECG diagnostic monitoring ... current and evolving indications -- 8.1 Introduction -- 8.2 Interpretation of results -- 8.3 In-hospital monitoring -- 8.3.1 Indications -- 8.4 Holter monitoring -- 8.5 External loop recorder (ELR) and remote at-home telemetry -- 8.5.1 Indications -- 8.6 Implantable loop recorder (ILR) -- 8.6.1 Natural history of syncope (probability of recurrence of syncope) in patients at low risk -- 8.6.2 Value of ILR in diagnosis of syncope -- 8.6.3 ILR in syncope -- where in the workup? -- 8.6.4 Indications -- 8.6.5 Classification of responses -- 8.5.7 Therapy guided by ILR -- 8.5.8 Technical aspects -- 8.6 Diagnostic yield of prolonged diagnostic monitoring in patients with uncertain syncope -- 8.7 Clinical perspectives -- Chapter 9. Syncope facilities: background and current standard -- 9.1 Background: why should we need a dedicated facility? -- 9.2 Some existing syncope facility models -- 9.2.1 Newcastle -- 9.2.2 Manchester -- 9.2.3 Controlled studies of patients presenting with syncope to the Emergency Department -- 9.3 The standards recommended by the ESC guidelines -- 9.3.1. Referral -- 9.3.2. Objectives -- 9.3.3. Professional skill mix for the Syncope Unit -- 9.3.4. Equipment -- 9.4 Clinical perspectives -- Chp 10 -- Syncope (T-LOC) Management Units: the Italian model -- 10.1 Introduction -- 10.2 The Italian Syncope Management Unit -- 10.2.1 Clinical results -- 10.2.2 Volume of activity -- 10.2.3 Referral -- 10.2.4 Diagnosis -- 10.2.5 Treatment -- 10.2.6 Hospitalization and cost analysis -- 10.3 Clinical perspectives -- SECTION ONE C -- Current evidence-based knowledge: Clinical Syndromes -- Diagnosis and Therapy -- Chapter 11. Reflex syncope (neurally-mediated syncope) 11.1 The wide clinical spectrum of an unique disorder 11.2 Diagnosis 11.3 Identifying the etiology of syncope 11.3.1 Vasovagal syncope 11.3.2 Situational syncope 11.3.3 Carotid sinus syncope 11.3.4 Atypical forms 11.3.5 Likely reflex (neurally-mediated) 11.4 Identifying the mechanism of syncope 11.4.1 ECG monitoring 11.4.2 Carotid sinus massage. 11.4.4 ATP (adenosine triphosphate) tests. 11.5 Therapy 11.5.1 Lifestyle measures 11.5.2 Additional treatments 11.5.3 Physical counterpressure maneuvers (PCM) 11.5.4 Tilt Training (Standing training) Method 11.5.5 Pharmacological Therapy 11.5.6 Cardiac Pacing 11.5.7 Conclusion 11.6 Clinical perspectives Chapter 12. Orthostatic Intolerance: Orthostatic Hypotension and Postural Orthostatic Tachycardia Syndrome 12.1 Introduction 12.2 Terminology 12.2.1 Orthostatic intolerance 12.2.2 Orthostatic hypotension (OH) 12.2.3 Postural Orthostatic Tachycardia Syndrome (POTS) 12.2.4 Dysautonomia 12.3 Physiology of Blood Pressure Control 12.4 Failure To Maintain Blood Pressure 12.5 Clinical Conditions 12.5.1 Orthostatic Syncope and Near-Syncope 12.5.2. Postural tachycardia syndrome (POTS) 12.6 Treatment of Orthostatic Intolerance 12.6.1 General measures 12.6.2 Non-pharmacological treatment strategies 12.6.3 Pharmacological treatment 12.7 Clinical perspectives Chapter 13. Cardiac Syncope 13.1 Introduction 13.2 Prognosis 13.3 Identifying a 'Cardiac origin' 13.4 Cardiac Conduction System Disease and Arrhythmias 13.4.1 Sinus node dysfunction (SND). 13.4.2 Atrioventricular conduction disorders 13.4.2 Supraventricular tachyarrhythmias 13.4.3 Ventricular tachycardias 13.5 Structural Cardiopulmonary Diseases 13.5.1 Myocardial Ischemia 13.5.2 Outflow Tract Obstruction 13.5.3 Other cardiopulmonary conditions that may cause syncope 13.6 Diagnostic Strategies 13.6.1 Evaluation In or Out of Hospital? 13.6.2 Specific Testing 13.7 Treatment 13.7.1 Addressing underlying structural disease as the treatment of syncope 13.7.2 Addressing underlying structural disease is not feasible or adequate 13.8 Clinical perspectives Chapter 14 Conditions that mimic syncope 14.1 Introduction 14.2 Syncope-Mimics and Pseudosyncope 14.3 Non-Syncope T-LOC 14.3.1 Epilepsy 14.3.2 Concussion 14.3.3 Metabolic and endocrine conditions mimicking syncope 14.4 Syncope / TLOC Mimic 14.4.1 Somatization Disorders (Pseudosyncope, 'Pseudoseizures') 14.4.2 Cataplexy 14.4.3 Hyperventilation 14.4.3 Transient ischemic attacks 14.5 Clinical perspectives Chapter 15
Summary Syncope has many possible causes, but the underlying mechanism of loss of consciousness is transient insufficiency of blood-flow to the brain. The result is a temporary disturbance of brain function causing loss of consciousness and collapse. By virtue of its being due to a self-limited hemodynamic problem resulting for example from a heart rhythm problem, or a drop in blood pressure of other cause, syncope differs from other conditions that cause loss of consciousness. A multidisciplinary approach is likely to be most effective for the evaluation and treatment of syncope; often the expertise of cardiologists, neurologists, emergency medicine specialists, general practitioners, geriatricians and other clinicians is needed. However, unfortunately, each of these sub-specialties have tended to develop and use different terminology, methodology and management guidelines; this has complicated effective interaction among these various care-givers, and has made evaluation and treatment of affected patients more complex. This volume, represents a thorough multidisciplinary review of the subject, offering recommendations based on the guidelines as well as experience derived from the various sub-specialties. It begins by discussing the scientific basis behind the diverse pathophysiology of conditions that may cause syncope, and reviews the optimal clinical management pathways. Later sections of the book then take a more practical approach, defining recommendations for the practice of syncope management through case examples. The most common procedures and tests are discussed along with their indications, methodology, interpretation, and limitations. This book has been designed to fulfill the needs of the wide range of medical practitioners involved in the care of syncope patients. All specialties will benefit from the concentration on the importance of medical history taking. Emergency room physicians and internists will be aided by the focus on risk stratification. Cardiologists and cardiac electrophysiologists will find up-to-date recommendations regarding the indications for and appropriate interpretation of noninvasive and invasive cardiac testing. Neurologists and psychiatrists will find useful the sections exploring the often difficult topic of distinguishing true syncope from other important conditions that may present as transient loss of consciousness
Analysis geneeskunde
medicine
volksgezondheid
public health
neurologie
neurology
noodgevallen
emergencies
cardiologie
cardiology
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Syncope (Pathology)
Evidence-based medicine.
Syncope -- diagnosis
Syncope -- therapy
Evidence-Based Medicine
Syncope
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Médecine.
Evidence-based medicine
Syncope (Pathology)
Form Electronic book
Author Benditt, David G.
ISBN 9780857292018
0857292013
0857292005
9780857292001