| Description |
1 online resource (electronic texts (645 pages)) : illustrations, digital files |
| Contents |
1. Ethics and privacy considerations for systems biology applications in predictive and personalized medicine / Jake Chen [and others] -- 2. Virtual screening / Khaled Barakat, Jonathan Mane, Jack Tuszynski -- 3. Systems biology-based approaches applied to vaccine development / Patricio Manque, Ute Woehlbier -- 4. Current Omics technologies in biomarker discovery / Wei Ding [and others] -- 5. Single nucleotide polymorphism and its application in mapping loci involved in developing human diseases and traits / Rui-Ru Ji -- 6. Addressing the challenges of detecting epistasis in genome-wide association studies of common human diseases using biological expert knowledge / Kristine Pattin, Jason Moore -- 7. Biclustering of DNA microarray data / Alain Tchagang [and others] -- 8. Prediction of epigenetic target sites by using genomic DNA sequence / Guo-Cheng Yuan -- 9. A new approach for sequence analysis / Kathryn Dempsey [and others] -- 10. Knowledge-driven, data-assisted integrative pathway analytics / Padmalatha Reddy, Stuart Murray, Wei Liu -- 11. Modules in biological networks / Bing Zhang, Zhiao Shi -- 12. Using functional linkage gene networks to study human diseases / Bolan Linghu, Guohui Liu, Yu Xia -- 13. Network-driven analysis methods and their application to drug discovery / Daniel Ziemek, Christoph Brockel -- 14. Pathway resources at the rat genome database / Victoria Petri |
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15. Unsupervised methods to identify cellular signaling networks from perturbation data / Madhusudan Natarajan -- 16. Complexity and modularity of MAPK signaling networks / George Popescu, Sorina Popescu -- 17. Cancer and signaling pathway deregulation / Yingchun Liu -- 18. Computational methods for identification of novel secondary metabolite biosynthetic pathways by genome analysis / Swadha Anand, Debasisa Mohanty -- 19. Linking interactome to disease / Maxime Garcia [and others] -- 20. Using systems biology approaches to predict new players in the innate immune system / Bin Li -- 21. Dynamic modeling and parameter identification for biological networks / Fortunato Bianconi, Gabriele Lillacci, Paolo Valigi -- 22. Granger causality / Tian Ge, Jianfeng Feng -- 23. Connecting microbial population genetics with microbial pathogenesis engineering microfluidic cell arrays for high-throughput interrogation of host-pathogen interaction / Palaniappan Sethu [and others] -- 24. Structural alignment of RNAs with pseudoknots / Thomas Wong, S. Yiu -- 25. Finding attractors on a folding energy landscape / Wilfred Ndifon, Jonathan Dushoff -- 26. Visualization of protein 3D structures in 'double-centroid' reduced representation / Vicente Reyes, Vrunda Sheth -- 27. Mechanical models of cell adhesion incorporating nonlinear behavior and stochastic rupture of the bonds / Jean-François Ganghoffer -- 28. A multiscale computational model of chemotactic axon guidance / Giacomo Aletti [and others] |
| Summary |
"This book offers information on the state-of-the-art development in the fields of computational biology and systems biology, presenting methods, tools, and applications of these fields by many leading experts around the globe"--Provided by publisher |
| Analysis |
Biclustering of DNA microarray data |
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Detecting epistasis in genome-wide association studies |
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DNA microarray data |
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Genomic DNA sequence |
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Granger causality |
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Predictive and personalized medicine |
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Privacy considerations for systems biology applications |
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Vaccine development |
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Virtual screening |
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Visualization of protein 3D structures |
| Bibliography |
Includes bibliographical references |
| Subject |
Computational biology -- Research
|
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Systems biology -- Research
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| Form |
Electronic book
|
| Author |
Liu, Limin Angela, 1974-
|
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IGI Global.
|
| LC no. |
2010035344 |
| ISBN |
9781609604929 |
|
160960492X |
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