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Book Cover
E-book

Title Advances in PET : the latest in instrumentation, technology, and clinical practice / Jun Zhang, Michael V. Knopp, editors
Published Cham, Switzerland : Springer, [2020]

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Description 1 online resource (xii, 107 pages)
Contents Intro -- Preface -- Contents -- Contributors -- Abbreviations -- Part I: Basics Science of Positron Emission Tomography -- 1: Current Status of PET Technology -- 1.1 Introduction -- 1.2 Current Status of TOF PET/CT Scanners -- 1.3 Hardware Design -- 1.3.1 Scintillator -- 1.3.2 Photosensor -- 1.3.3 Detector Design -- 1.4 Software Algorithms -- 1.5 Conclusion -- References -- 2: Current Status and Future Directions of PET in Clinical Practice -- 2.1 FDG PET/CT -- 2.1.1 Neuroimaging -- 2.1.2 Cardiac Imaging -- 2.1.3 Oncologic Imaging -- 2.1.4 Infection/Inflammation
2.1.5 Myocardial Perfusion Imaging -- 2.1.6 Amyloid Imaging -- 2.1.7 Somatostatin Receptor Imaging -- 2.2 PET/MR -- 2.3 Future Directions -- 2.4 Conclusion -- References -- Part II: Solid State Digital PET Instrumentation, Technology and Clinical Practice -- 3: Introduction to Silicon Photomultipliers for Time-of-Flight PET -- 3.1 Introduction -- 3.2 TOF-PET Photosensor Requirements -- 3.3 Vacuum Photomultipliers -- 3.4 Solid-State Photomultipliers -- 3.4.1 Introduction to Silicon Photomultipliers -- 3.4.2 SiPM Single-Photon Signal Shape
3.4.3 Time Resolution of SiPM-Based Scintillation Detectors -- 3.4.4 Digital SiPMs -- References -- 4: New-Generation Silicon Photomultiplier-Based Clinical PET/CT and PET/MR Systems -- 4.1 Introduction to Multimodal PET Imaging Systems -- 4.2 Clinically Driven PET System Design Trends -- 4.2.1 Time-of-Flight Performance -- 4.2.2 Multimodality PET Detector Modules -- 4.2.3 Temperature Stability -- 4.2.4 Improving Noise-Equivalent Count Rates -- 4.2.5 Summary -- 4.3 SiPM-Based Block Detector Architecture -- 4.4 Performance Characterization and Discussion -- 4.4.1 NEMA Characterization
4.4.2 Clinical Instrumentation and Imaging Comparisons -- 4.5 Conclusion -- References -- 5: Solid-State Digital Photon Counting PET/CT -- 5.1 Introduction -- 5.2 Architecture -- 5.2.1 Hardware -- 5.2.2 Philips Digital Photon Counting (PDPC) -- 5.3 Reconstruction -- 5.4 Quality Control -- 5.5 System Performance Measurements -- 5.5.1 Spatial Resolution -- 5.5.2 Sensitivity -- 5.5.3 NECR and Count Performance -- 5.5.4 TOF Timing Resolution -- 5.6 Clinical Applications -- 5.6.1 Low-Dose PET -- 5.6.2 Fast PET Scanning -- 5.6.3 Low Counts Density PET Simulation
5.6.4 Lesion Detectability -- 5.7 Conclusion -- References -- 6: Siemens Biograph Vision 600 -- 6.1 Introduction -- 6.2 Architecture -- 6.3 Data Processing -- 6.3.1 Data Organization -- 6.3.2 Reconstruction -- 6.3.3 Randoms -- 6.3.4 Normalization -- 6.3.5 Scatter -- 6.3.6 Attenuation Correction -- 6.3.7 Continuous Bed Motion -- 6.4 Performance -- 6.4.1 Spatial Resolution -- 6.4.2 Sensitivity -- 6.4.3 True, Scatter, and Random Rates -- 6.4.4 Time Resolution -- 6.4.5 Image Quality -- 6.5 Clinical Applications -- 6.5.1 Continuous Bed Motion -- 6.5.2 Respiratory and Cardiac Gating
Summary This book is a guide to new and emerging PET technology, instrumentation, and its place in clinical practice. PET technology is currently moving from the conventional photomultiplier tube (PMT) detector based PET to the new generation, solid state light sensor detector. This is a technological leap and holds significant implications for the use of PET imaging. This book introduces and describes the emerging and new generation of PET instrumentations and technologies across manufactures, focusing on solid-state PET detector designs, system characteristics, and clinical practices as well as future advanced Time-of-Flight (TOF) PET technologies. Organized into three sections, the basics of PET imaging; solid state digital PET instrumentation, technology, and clinical practice; and a look to the future of PET imaging, chapters present a full picture of PET imaging, where we are and where we will be. Nuclear medicine physicians, physicists, and technologists can use this book to better understand future PET systems, novel PET technologies, and potential game changes of clinical PET practice
Notes Description based upon print version of record
Bibliography Includes bibliographical references and index
Subject Tomography, Emission.
Tomography, Emission-Computed
Radiology.
Nuclear medicine.
Medical -- Diagnostic Imaging.
Medical -- Radiology & Nuclear Medicine.
Tomography, Emission
Form Electronic book
Author Zhang, Jun, editor
Knopp, Michael V.
ISBN 9783030430405
3030430405