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Book Cover
Streaming video
Author Shilatifard, Ali, (Stowers Institute, USA), speaker

Title Enhancer malfunction in cancer / Ali Shilatifard
Published London : Henry Stewart Talks, 2014
Online access available from:
HSTalks Biomedical & Life Sciences Collection    View Resource Record  


Description 1 online resource (1 streaming video file (41 min.) : color, sound)
Series Epigenetics, chromatin, transcription and cancer, 2056-452X
Henry Stewart talks. Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer
Contents Contents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? -- Why do translocations of MLL with so many different partners result in leukemogenesis? -- The AFF4 complex and Hox genes -- COMPASS family of H3K4 methylases and their mutations in cancer -- Chromatin Bivalency -- The ELL family of Pol II elongation factors -- Drosophila Trr -- Enhancer/promoter interactions, malfunctions and their outcomes
Notes Animated audio-visual presentation with synchronized narration
Title from title frames
Mode of access: World Wide Web
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Subject Cancer cells.
Genetic regulation.
Leukemia -- Genetic aspects.
Cell Transformation, Neoplastic.
Chromatin -- genetics.
Gene Expression Regulation.
Histone-Lysine N-Methyltransferase.
Leukemia -- genetics.
Myeloid-Lymphoid Leukemia Protein.
Neoplasms -- genetics.
Transcriptional Elongation Factors -- metabolism.
Genre/Form Video recordings.
Form Streaming video