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Title Analyzing T cell responses : how to analyze cellular immune responses against tumor associated antigens / edited by Dirk Nagorsen and F.M. Marincola
Published Dordrecht, the Netherlands : Springer, [2005]
©2005
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Description 1 online resource (xii, 313 pages) : illustrations (some color)
Contents Monitoring Antigen-Specific T Cell Responses / Dirk Nagorsen, Francesco M. Marincola -- Tumor Associated Antigens / Paul F. Robbins -- Immune Escape -- Tumor induced immune suppression and immune escape : Mechanisms and Possible Solutions / Theresa L. Whiteside, Michael Campoli, Soldano Ferrone -- Virus Specific T-Cell Responses / Victor Appay -- Cytotoxicity Assays -- Killer Lymphocytes in Cancer / Gideon Berke, William R. Clark -- Monitoring T Cell Proliferation / Philip D. Hodgkin [and others] -- Elispot assay -- Assessment of Cellular Immune Responses to Anti-Cancer Vaccines / Theresa L. Whiteside -- Modified Elispot -- Modifications of the Elispot Assay for T Cell Monitoring in Cancer Vaccine Trials / Anatoli Malyguine -- Intracellular Cytokine Staining -- Cytokine flow cytometry for characterization of tumor-specific T cell responses / Carmen Scheibenbogen [and others] -- Cytometric Cytokine Secretion Assay -- Detection and Isolation of Antigen-Specific T Cells / Mario Assenmacher -- Peptide/MHC Tetramer Analysis / Peter P. Lee, Francesco M. Marincola -- In Situ MHC Tetramer Staining -- In situ tetramers / Pamela J. Skinner -- MHC-IG Dimeric Molecules -- Dimers -- MHC-Ig dimeric molecules for the analysis of antigen-specific T cell responses / Tim F. Greten, Firouzeh Korangy -- TCR Analyses -- T-cell receptor CDR3 analysis : Molecular fingerprinting of the T-cell receptor repertoire / Markus J. Maeurer -- Peptide/HLA-GFP Complexes -- Detection of Antigen-Specific T Cells by Acquisition of Peptide/Hla-Gfp Complexes / Utano Tomaru, Yoshihisa Yamano, Steven Jacobson -- QRT-PCR -- Quantitative RT-PCR for the Analysis of T cell Responses in Immunized Cancer Patients / Udai S. Kammula -- Microarrays -- Gene expression profiling approaches for the monitoring of anti-cancer immune responses / Ena Wang -- Concluding Remark / Dirk Nagorsen, Francesco M. Marincola
Summary Emphasizing a global approach to the analysis of T cell mediated target/host interactions at the systemic and the peripheral level when such interactions are supposed to occur, this book provides a critical assessment of the assays that have been used for the monitoring of antigen-specific immune responses
Bibliography Includes bibliographical references and index
Subject Cellular immunity.
T cells -- Immunology.
Tumor antigens.
T-Lymphocytes -- immunology.
Antigens, Neoplasm -- analysis.
Antigens, Neoplasm -- immunology.
Immunity, Cellular.
T-Cell Antigen Receptor Specificity.
Form Electronic book
Author Marincola, Francesco M.
Nagorsen, Dirk.
LC no. 2007280519
ISBN 1402036221 (hd. bd. ; alk. paper)
140203623X (e-book)
9781402036224 (hd. bd. ; alk. paper)
9781402036231 (e-book)