| Description |
1 online resource (xix, 198 pages) : color illustrations |
| Contents |
Intro; Preface; Contents; Abstract; Abbreviations and Anacronyms; Acknowledgments; About the Author; Chapter 1: Introduction; 1.1 Concepts; 1.2 Differences of Drug Metabolism in Neonates and in Infants; 1.3 Chemotherapy in Neonates and Infants; 1.4 Statistics on Diseases in Neonates and Infants; 1.5 Concepts of Oncohematology Treatment of Neonates and Infants; 1.5.1 Congenital Tumors; 1.5.2 Teratomas; 1.5.3 Neuroblastoma; 1.5.4 Central Nervous System Tumors; 1.5.5 Leukemias; 1.5.6 Renal Tumors; 1.5.7 Hepatic Tumors; 1.5.8 Other Tumors |
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Chapter 2: Protocols Used in Chemotherapy Treatment of Neonates and Infants2.1 Acute Lymphoblastic Leukemia/Biphenotypic Leukemia; 2.1.1 Interfant-06 Protocol for Infants Younger than 1 Year with Acute Lymphoblastic Leukemia or Biphenotypic Leukemia; 2.1.2 BFM95 (Berlin-Frankfurt-Münster) Protocol for Children Under 1 Year Old with Acute Lymphoid Leukemia; 2.2 Acute Myeloid Leukemia; 2.2.1 AIEOP 2002/01 Protocol for Children Under 1 Year Old with Acute Myeloid Leukemia; 2.3 Central Nervous System |
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2.3.1 CCG-9921 Protocol for Children Younger than 36 Months with Malignant Brain Tumor, Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, Ependymoma, or Rhabdoid Tumor2.4 Wilms' Tumor; 2.4.1 Protocol with Vincristine Used as a Single Agent in a 3-Week-Old Neonate; 2.5 Hepatoblastoma; 2.5.1 Protocol with Cisplatin Used as a Single Agent in a 2-Week-Old Neonate; 2.6 Retinoblastoma; 2.6.1 Guideline for Retinoblastoma Treatment of Preterm and Full-Term Neonates up to 3 Weeks Old, Including Carboplatin; 2.7 Neuroblastoma |
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2.7.1 Case of a Neonate (Gestational Age 40 Weeks) Diagnosed at 3 Days of Age with Low-Risk Localized Unresectable NeuroblastomaChapter 3: Pharmacokinetics and Pharmacodynamics of Chemotherapy Drugs in Neonates and Infants; 3.1 Pharmacokinetics of Chemotherapy Drugs in Neonates and Infants; 3.1.1 Absorption of Chemotherapy in Neonates and Infants; 3.1.1.1. Drug Absorption in Neonates; Oral Drug Absorption in Neonates; Dermal Drug Absorption in Neonates; Intramuscular Drug Absorption in Neonates; Rectal Drug Absorption in Neonates; Absorption and Bile and Pancreas Activity in Neonates |
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3.1.1.2. Drug Absorption in InfantsOral Drug Absorption in Infants; Intramuscular Drug Absorption in Infants; Absorption and Bile and Pancreas Activity in Infants; 3.1.2 Excretion of Chemotherapy in Neonates and Infants; 3.1.2.1. Drug Excretion in Neonates; 3.1.2.2. Drug Excretion in Infants; 3.1.3 Drug Binding and Distribution by Proteins in Neonates and Infants; 3.1.3.1. Binding Proteins; Binding Proteins in Neonates; Binding Proteins in Infants; 3.1.3.2. Transport Proteins; ABC Transporters; Solute Carriers; Transport Proteins in Neonates and Infants |
| Summary |
This book provides a comprehensive overview of pediatric oncology, discussing drug therapy and treatment in children under the age of 1 year. It is the first volume to focus on chemotherapy in newborns and infants, especially the daily clinical practice and treatment protocols. Intended as a practical manual, it addresses all the major topics related to pediatric oncology in an accessible and easy-to-use format. It examines topics in pediatric oncology therapeutics, including drug metabolism, excretion, toxicity, drugs that can be used for each week or month of the patient's life, dose adjustment and treatment protocols. Chemotherapy in Neonates and Infants focuses on the safe treatment of children in the first year of life, and is aimed at pediatric oncology/hematology institutions, clinics and departments. It is particularly valuable for researchers, pediatric oncology physicians, pediatric and neonatology physicians, oncology pharmacists and the other healthcare professionals directly involved in the chemotherapy of neonates and infants |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed April 18, 2018) |
| Subject |
Tumors in children -- Chemotherapy -- Handbooks, manuals, etc
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Chemotherapy.
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Children.
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Drug Therapy
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Neoplasms
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Child
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children (people by age group)
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Oncology.
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Haematology.
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Pharmacology.
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Paediatric medicine.
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MEDICAL -- Gynecology & Obstetrics.
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Children
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Chemotherapy
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Tumors in children -- Chemotherapy
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| Genre/Form |
handbooks.
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Handbooks and manuals
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Handbooks and manuals.
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Guides et manuels.
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| Form |
Electronic book
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| ISBN |
9783319705910 |
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3319705911 |
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