| Description |
1 online resource (vii, 157 pages) : illustrations |
| Series |
Current topics in microbiology and immunology, 0070-217X ; 303 |
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Current topics in microbiology and immunology ; 303. 0070-217X
|
| Contents |
Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system / T.E. Lane, J.L. Hardison, and K.B. Walsh -- Cytokine and chemokine networks : pathways to antiviral defense / T.P. Salazar-Mather and K.L. Hokeness -- Herpes simplex virus and the chemokines that mediate the inflammation / D.J.J. Carr and L. Tomanek -- Influence of proinflammatory cytokines and chemokines on the neuropathogenesis of oncornavirus and immunosuppressive lentivirus infections / K.E. Peterson and B. Chesebro -- HIV-1 coreceptors and their inhibitors / N. Ray and R.W. Doms -- A viral conspiracy : hijacking the chemokine system through virally encoded pirated chemokine receptors / H.F. Vischer, C. Vink, and M.J. Smit |
| Summary |
This edition of Current Topics in Microbiology and Immunology examines the role of chemokines and chemokine receptors in host defense and disease development following viral infection. Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue. There are now four sub-families of chemokines identified based on defined structural criteria relating to the positional location of conserved cysteine residues within the amino-terminus of the protein. Chemokines are now recognized as important in numerous biological processes ranging from maintaining the organizational integrity of secondary lymphoid tissue to participating in various aspects of both innate and adaptive immune responses following microbial infection. With this in mind, this book highlights the functional roles of chemokines and their receptors in participating in various aspects of the immune response against well-known viral pathogens |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer e-books |
| Subject |
Chemokines.
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Virus diseases.
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Microbiology.
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Chemokines -- immunology
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Chemokines
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Virus Diseases
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Receptors, Chemokine -- immunology
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Virus Diseases -- immunology
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Microbiology
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microbiology.
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MEDICAL -- Infectious Diseases.
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HEALTH & FITNESS -- Diseases -- Contagious.
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Chemokines.
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Virus diseases.
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Biomédecine.
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Sciences de la vie.
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Chemokines
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Virus diseases
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| Form |
Electronic book
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| Author |
Lane, T. E. (Thomas E.)
|
| ISBN |
9783540333975 |
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3540333975 |
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3540292071 |
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9783540292074 |
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6610866015 |
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9786610866014 |
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