| Description |
1 online resource (xv, 559 pages) : illustrations |
| Series |
Handbook of experimental pharmacology ; v. 200 |
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Handbook of experimental pharmacology ; v. 200.
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| Contents |
Notes on the history of caffeine use -- Distribution, biosynthesis and catabolism of methylxanthines in plants -- Pharmacokinetics and metabolism of natural methylxanthines in animal and man -- Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds -- Methylxanthines and ryanodine receptor channels -- Xanthines as adenosine receptor antagonists -- Theobromine and the pharmacology of cocoa -- Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain -- Methylxanthines, seizures, and excitotoxicity -- Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies -- Methylxanthines and pain -- Methylxanthines and sleep -- Methylxanthines and reproduction -- Methylxanthines during pregnancy and early postnatal life -- Methylxanthines and the kidney -- Cardiovascular effects of methylxanthines -- Methylxanthines in asthma -- Methylxanthines and inflammatory cells -- Methylxanthines, inflammation, and cancer: fundamental mechanisms -- Methylxanthines and drug dependence: a focus on interactions with substances of abuse -- Methylxanthines and human health: epidemiological and experimental evidence |
| Summary |
In the present volume of the Handbook of Experimental Pharmacology well known experts describe the actions of different xanthines with a focus on caffeine and theophylline. A special chapter is devoted to theobromine, an active component of chocolate, the actions of which are less well characterized. This book also presents the pharmacology of one xanthine derivative, propentofylline, as an example of a xanthine that has gone through extensive development for a novel therapeutic area |
| Analysis |
farmacologie |
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pharmacology |
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toxicologie |
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toxicology |
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neurochemie |
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neurochemistry |
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biochemie |
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biochemistry |
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biomedische wetenschappen |
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biomedicine |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| In |
Springer eBooks |
| Subject |
Methylxanthines.
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Xanthine.
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Toxicology.
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Biochemistry.
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Xanthines
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Toxicology
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Biochemistry
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toxicology.
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biochemistry.
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MEDICAL -- Pharmacology.
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Xanthine
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Methylxanthines
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Methylxanthine
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| Genre/Form |
Aufsatzsammlung.
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| Form |
Electronic book
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| Author |
Fredholm, B. B.
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| LC no. |
2010935195 |
| ISBN |
9783642134432 |
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3642134432 |
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