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Book Cover
Author Chappell, Michael, author

Title Introduction to perfusion qualification using arterial spin labeling / Michael Chappell, Bradley MacIntosh, Thomas Okell
Published Oxford : Oxford University Press, 2018
Online access available from:
Oxford Scholarship Online    View Resource Record  


Description 1 online resource
Series Oxford neuroimaging primers
Oxford neuroimaging primers
Contents Introduction -- ASL acquisition principles -- Preprocessing -- Kinetic modelig -- Calibration: estimating arterial blood magnetization -- Partial volume effects -- Using ASL to measure perfusion changes in an individual: task-based ASL and beyond -- Using ASL to measure perfusion in and between groups of individuals
Summary Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is unique in being a completely non-invasive method for imaging perfusion in the brain. Relying upon a blood-borne tracer that is created by the MRI scanner itself, ASL is becoming a popular tool to study cerebral perfusion, as well as how this perfusion changes in response to neuronal activity or in disease. This primer provides an introduction to perfusion quantification using ASL MRI, focusing both on the methods needed to extract perfusion-weighted images and on how to quantify perfusion and other hemodynamic parameters. Starting with the simplest implementation of ASL, the primer details all the common acquisition methods, as well as the subsequent analysis steps required to quantify perfusion in an individual, detect changes in perfusion in response to neural activity or pharmacological intervention, and examine perfusion variations across groups of individuals. This is supported with examples from real data illustrating all the major steps in the analysis process, linked to online material where the reader can undertake the same analysis for themselves
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Brain -- Imaging
Brain -- Imaging.
Genre/Form Ebook added
Form Electronic book
Author MacIntosh, Bradley, author
Okell, Thomas, author
UPSO (University Press Scholarship Online)
ISBN 0191835617 (electronic bk.)
9780191835612 (electronic bk.)