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Book Cover
Book
Author Grahame-Smith, David Grahame, author

Title Oxford textbook of clinical pharmacology and drug therapy / D.G. Grahame-Smith and J.K. Aronson
Edition Third edition
Published Oxford ; New York : Oxford University Press, 2002
Oxford : Oxford University Press, 2006
©2002

Copies

Location Call no. Vol. Availability
 W'PONDS  615.58 Gra/Oto 2002  AVAILABLE
 MELB  615.58 Gra/Oto 2002  AVAILABLE
Description xiv, 641 pages : illustration ; 28 cm
Contents Machine derived contents note: Section 1 -- 1. The four processes of drug therapy -- 1.2. The pharmacokinetic process -- 2. The pharmaceutical process: Is the drug getting into the patient? -- 2.2. Systematic availability (bioavailability) -- 2.3. Special drug formulations -- 3. The pharmacokinetic process: Is the drug getting to its site of action? -- 3.2. Drug distribution -- 3.3. Drug metabolism -- 3.4. Drug excretion -- 3.5. Simple pharmacokinetic calculations -- 3.6. The mathematics of pharmacokinetics -- 4. The pharmacodynamic process: Is the drug producing the required pharmacological effect? -- 4.2. Stereoisomerism and drug action -- 4.3. Graded responses to drugs: the dose-response curve in drug therapy -- 5. The therapeutic process: Is the pharmacological effect being translated into therapeutic effect? -- 5.2. Translation of the pharmacological effect of a drug into a therapeutic effect during long-term drug therapy -- 5.3. The aims of drug therapy -- 6. Practical applications of the analysis of drug therapy -- 6.2. The application of the processes of drug therapy in analysing failure to respond to treatment -- 7. Monitoring drug therapy -- 7.2. Monitoring the pharmacodynamic effects of drugs -- 7.3. Monitoring drug pharmacokinetics (plasma concentration measurement) -- 8. Pharmacogenetics and pharmacogenomics -- 8.2. Pharmacodynamic genetic variations -- 9. Adverse reactions to drugs -- 9.2. Incidence of adverse drug reactions -- 9.3. Classification of adverse drug reactions -- 9.4. Dose-related adverse drug reactions -- 9.5. Non-dose-related adverse drug reactions -- 9.6. Long-term and withdrawal effects causing adverse drug reactions -- 9.7. Delayed effects causing adverse drug reactions -- 9.8. Surveillance methods used in detecting adverse drug reactions -- 10. Drug interactions -- 10.2. Drugs likely to be involved in interactions -- 10.3. Pharmaceutical interactions -- 10.4. Pharmacokinetic interactions -- 10.5. Pharmacodynamic interactions -- 10.6. Lists clinically important drug interactions -- 11. Drug therapy in young and in old people -- 11.2. Drug therapy in old people -- 12. Drug therapy and reproduction -- 12.2. Hormone replacement therapy -- 12.3. The treatment of infertility -- 12.4. Drug therapy during pregnancy -- 12.5. Drug therapy in the termination of pregnancy and in the management of preterm labour and labour -- 12.6. Drug therapy and breast-feeding -- 13. Patient compliance -- 13.2. Methods of measuring compliance -- 13.3. Methods of improving compliance -- 14. Placebos -- 14.2. Factors that influence the response to placebos -- 14.3. Mode of action of placebos -- 14.4. Adverse effects of placebos -- 15. Drug discovery and development: the pharmaceutical industry and the regulatory authorities -- 15.2. Drug development -- 15.3. Post-marketing surveillance -- 15.4. Advertising -- 15.5. Regulatory authorities -- 15.6. Local drug and therapeutics committees -- 15.7. Drug costs -- 16. Clinical trials -- 16.2. The conduct of a clinical trial -- 16.3. Ethics -- 17. The drug history and the clinical examination and investigation of drug effects -- 17.1. Taking the drug history -- 17.2. Clinical examination and investigation of drug effects -- 17.3. The importance of good records and communication -- Section 2 -- 18. Principles of prescribing -- 18.2. Evidence - based medicine -- 18.3. How to choose a drug -- 19. How to write a prescription -- 19.2. Propriety names versus approved names -- 19.3. Prescribing controlled drugs -- 19.4. Repeat prescribing -- 19.5. Abbreviations -- 20. Sources of information on drugs -- 20.2. Pharmacokinetics -- 20.3. Pharmacological effects of drugs -- 20.4. Therapeutics -- 20.5. Pharmacogenetics -- 20.6. Adverse effects of drugs -- 20.7. Drug interactions -- 20.8. Clinical trials -- 20.9. Patient compliance -- 20.10. Prescribing information -- 20.11. Computerised databases -- 20.12. Drug information services -- 20.13. Bibliography -- Section 3 -- 21. Introduction to drug therapy -- 22.2. Chemotherapy of viral infections
Notes Previous ed.: 1992
Includes index
Bibliography Includes bibliographical references and index
SUBJECT Clinical pharmacology. http://id.loc.gov/authorities/names/n83708030
Subject Pharmacology.
Chemotherapy.
Clinical pharmacology.
Pharmacology, Clinical.
Drug Therapy.
Drug Therapy.
Pharmacology, Clinical.
Author Aronson, J. K., author
LC no. 2003265338
ISBN 0198509448
0192632345 (paperback)
Other Titles Textbook of clinical pharmacology and drug therapy
Clinical pharmacology and drug therapy
Textbook of clinical pharmacology and drug therapy
Clinical pharmacology and drug therapy