| Description |
1 online resource (x, 512 pages) : illustrations (some color) |
|
1 CD-ROM |
| Series |
Biotechnology: pharmaceutical aspects |
|
Biotechnology (Arlington, Va.)
|
| Contents |
Front Matter; Strategic Use of Preclinical Pharmacokinetic Studies and In Vitro Models in Optimizing ADME Properties of Lead Compounds; Role of Mechanistic Transport Studies in Lead Optimization; Metabolic Activation-Role in Toxicity and Idiosyncratic Reactions; Case History -- Use of ADME Studies for Optimization of Drug Candidates; Solubility, Solubilization and Dissolution in Drug Delivery During Lead Optimization; Lipid-based Systems, Drug Exposure and Lead Optimization; Biopharmaceutics Modeling and the Role of Dose and Formulation on Oral Exposure |
| Summary |
Based on the workshop, entitled "Pharmaceutical Profiling in Drug Discovery for Lead Selection", which took place in Whippany, on May 19-21, 2003. The workshop was focused on prediction, measurement, and utilization of drug-like properties during lead selection |
| Analysis |
farmacologie |
|
pharmacology |
|
toxicologie |
|
toxicology |
|
biomedische wetenschappen |
|
biomedicine |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Drugs -- Design.
|
|
Drug development.
|
|
Pharmaceutical chemistry.
|
|
Toxicology.
|
|
Chemistry, Pharmaceutical -- methods
|
|
Drug Design
|
|
Drug Discovery
|
|
Chemistry, Pharmaceutical
|
|
Toxicology
|
|
medicines (material)
|
|
toxicology.
|
|
MEDICAL -- Drug Guides.
|
|
MEDICAL -- Pharmacology.
|
|
MEDICAL -- Pharmacy.
|
|
MEDICAL -- Nursing -- Pharmacology.
|
|
Biomédecine.
|
|
Sciences de la vie.
|
|
Drug development
|
|
Drugs -- Design
|
|
Pharmaceutical chemistry
|
| Form |
Electronic book
|
| Author |
Borchardt, Ronald T.
|
| LC no. |
2006927190 |
| ISBN |
9780387449616 |
|
0387449612 |
|
9780387340562 |
|
0387340564 |
|
