Book Cover
Streaming video
Author Rogge, Mark C., speaker

Title Pharmacokinetics, toxicokinetics & safety margins / Mark C. Rogge
Published London : Henry Stewart Talks, 2009
Online access available from:
Henry Stewart Talks: Biomedical & Life Sciences Lectures    View Resource Record  


Description 1 online resource (1 streaming video file (43 min.) : color, sound)
Series Non-clinical testing for toxicity of pharmaceuticals : regulatory and practical standards for testing and application, 2056-452X
Henry Stewart talks. Biomedical & life sciences collection. Non-clinical testing for toxicity of pharmaceuticals
Contents Contents: The pharmacologic and toxic effects of a potential therapeutic agent are a consequence of the product concentration at the site of action -- By understanding inter-species sensitivity to the agent and to the absorption and disposition properties, a rational first in human dose can be determined -- Basic pharmacokinetic elements -- Measures of exposure -- Scaling methods and calculations of relative exposure -- Utilizing outcomes from toxicology evaluations and associated exposure measures -- First in human dose concept
Notes Animated audio-visual presentation with synchonized narration
Title from title frames
Mode of access: World Wide Web
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
Subject Drug Toxicity.
Toxicity Tests.
Genre/Form Video recordings.
Form Streaming video
Other Titles Pharmacokinetics, toxicokinetics and safety margins