| Description |
1 online resource (xx, 369 pages) : illustrations (some color), portrait |
| Contents |
I. Neurological disorders -- epidemiology, clinical overview, and model systems. 1. Stroke / Andreas Meisel [and others] -- Parkinson's disease / Marina Romero-Ramos, Matthew Maingay and Deniz Kirik -- Amyotrophic lateral sclerosis / Georg Haase -- Alzheimer's disease and other neurodegenerative diseases / Philipp J. Kahle and Christian Haass -- CNS inflammation / Christine Stadelmann and Wolfgang Brück -- Neurotrauma / Ibolja Cernak, Paul M. Lea IV, Alan I. Faden -- Spinal cord injury / Poonam Verma and James W. Fawcett -- II. Cellular and molecular mechanisms. Apoptosis and necrosis / Laura Korhonen and Dan Lindholm -- Inflammation / Harald Neumann -- Metabolic dysfunctions / Konstantin A. Hossmann -- Protein misfolding / Milene Russelakis-Carneiro [and others] -- Axonal growth inhibition / Anne d. Zurn and Christine E. Bandtlow -- Neurogenesis / Sebastian Jessberger and Gerd Kempermann -- Excitotoxicity / Stuart A. Lipton -- Spinal cord trauma / V. Dietz -- Neurodegeneration / Jörg B. Schulz -- Perspectives for neuroprotective therapies in basic research and clinical application / Mathias Bähr and Pawel Kermer |
| Summary |
In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current ch |
| Analysis |
Molecular Biology and Genetics |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Molecular neurobiology.
|
|
Nervous system -- Diseases -- Treatment.
|
|
Disease Models, Animal.
|
|
Molecular Biology.
|
|
Nervous System Diseases -- therapy.
|
|
Neurodegenerative Diseases -- therapy.
|
|
Neuroprotective Agents -- pharmacology.
|
| Form |
Electronic book
|
| Author |
Bähr, Mathias.
|
| LC no. |
2004302823 |
| ISBN |
3527308164 (hbk.) |
|
3527603867 (electronic bk.) |
|
3527604316 (electronic bk.) |
|
9783527308163 (hbk.) |
|
9783527603862 (electronic bk.) |
|
9783527604319 (electronic bk.) |
|
