Book Cover

Title DNA pharmaceuticals : formulation and delivery in gene therapy, DNA vaccination and immunotherapy / edited by Martin Schleef
Published Weinheim : Wiley-VCH, [2005]
Online access available from:
Wiley Online Books    View Resource Record  


Description 1 online resource (xxii, 253 pages) : illustrations (some color)
Contents DNA Pharmaceuticals; Preface; Contents; List of Contributors; Abbreviations; 1 DNA Vaccines -- An Overview; 2 DNA as a Pharmaceutical -- Regulatory Aspects; 3 From Bulk to Delivery: Plasmid Manufacturing and Storage; 4 Minimized, CpG-Depleted, and Methylated DNA Vectors: Towards Perfection in Nonviral Gene Therapy; 5 Localized Nucleic Acid Delivery: A Discussion of Selected Methods; 6 DNA Needle Injection; 7 Needleless Jet Injection of Naked DNA for Nonviral in vivo Gene Transfer; 8 Plasmid Inhalation: Delivery to the Airways; 9 Hydrodynamic Gene Delivery
Summary With its focus on a completely novel class of pharmaceuticals, this book collates the hitherto scarce literature about DNA drug formulation keenly desired by biotechnologists, molecular biologists and pharmacists, as well as those working in the biotechnological and pharmaceutical industries. As such, this volume presents a wide range of gene delivery systems needed for different therapeutic applications. It fills the gap between research and clinical trials and describes pharmaceutical fundamentals for the development of efficient DNA pharmaceuticals
Bibliography Includes bibliographical references and index
Notes Print version record
Subject DNA vaccines.
Gene therapy.
Genetic Therapy.
Pharmaceutical Preparations -- administration & dosage.
Vaccines, DNA -- administration & dosage.
Form Electronic book
Author Schleef, M. (Martin)
John Wiley & Sons.
ISBN 128085409X
3527311874 (alk. paper)
3527607005 (electronic bk.)
3527607536 (electronic bk.)
9783527311873 (alk. paper)
9783527607006 (electronic bk.)
9783527607532 (electronic bk.)