| Description |
1 online resource (xxi, 314, [24] pages) : illustrations |
| Series |
Drug discovery series ; 11 |
| Contents |
Introduction to gene expression profiling with DNA microarray technology / Michael D. Kane -- Introduction to large-scale gene expression data analysis / Anbarasu Lourdusamy [and others] -- The statistical design and analysis of gene expression data / Sonia Jain -- Laboratory automation for microarray experimentation / Doug Gurevitch -- How to evaluate a microarray scanner / Yaping Zong [and others] -- The role of substrates in microarray experimentation and how to choose the correct coating for microarraying / Ruediger Dietrich [and others] -- Towards highly efficient automated hybridizations / Kris Pappaert [and others] -- Characterization of hybridization stoichiometry using a noncompetitive microarray assay / Richard J.D. Rouse and Gary Hardiman -- Data normalization selection / Phillip Stafford -- Methods for assessing microarray performance / Steffen G. Oeser [and others] -- Comparison of different normalization methods for applied biosystems expression array system / Catalin Barbacioru [and others] |
|
A systematic comparison of gene expression measurements across different hybridization-based technologies / Winston Patrick Kuo [and others] -- DNA methylation arrays : methods and analysis / N.P. Thorne [and others] -- Electronic microarrays : progress toward DNA diagnostics / Howard Reese [and others] -- New applications for microarrays / Mark Andersen, Christopher Adams, and Pete Jozsi -- Development of an oligonucleotide microarray for mutational analysis using single or multiple sample hybridization / Il-Jin Kim, Hio Chung Kang, and Jae-Gahb Park -- Development of an integrated molecular diagnostic test to identify respiratory viruses / Frédéric Raymond, Whei-Kuo Wu, and Jacques Corbeil -- Microarrays in neuroscience / Massimo Ubaldi [and others] -- Optimization of protein array fabrication for establishing high throughput ultra-sensitive microarray assays for cancer research / Gary Hardiman, C. Ramana Bhasker, and Richard J.D. Rouse |
| Summary |
In recent years, high-density DNA microarrays have revolutionized biomedical research and drug discovery efforts by the pharmaceutical industry. Their efficacy in identifying and prioritizing drug targets based on their ability to confirm a large number of gene expression measurements in parallel has become a key element in drug discovery |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
DNA microarrays.
|
|
Gene expression.
|
|
Gene Expression
|
|
DNA microarrays
|
|
Gene expression
|
| Form |
Electronic book
|
| Author |
Hardiman, Gary, 1966-
|
| ISBN |
9781420094510 |
|
1420094513 |
|
