| Description |
1 online resource (vi, 275 pages) : illustrations (some color) |
| Series |
Contributions to nephrology ; vol. 152 |
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Contributions to nephrology ; v. 152.
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| Contents |
Cell volume regulatory mechanisms an introduction / Friedrich, B., Matskevich, I., Lang, F. -- Cell volume-sensitive chloride channels : phenotypic properties and molecular identity / Okada, Y. -- Cell volume-regulated cation channels / Wehner, F. -- Sensors and signal transduction pathways in vertebrate cell volume regulation / Hoffmann, E.K., Pedersen, S.F. -- Activation of kinases upon volume changes : role in cellular homeostasis / Alexander, R.T., Grinstein, S. -- Tonicity dependent regulation of osmoprotective genes in mammalian cells / Ferraris, J.D., Burg, M.B. -- Ion channels and cell volume in regulation of cell proliferation and apoptotic cell death / Lang, F., Shumilina, E. [and others] |
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Cell volume regulatory ion transport in the regulation of cell migration / Jakab, M., Ritter, M. -- Cell volume regulation in the renal papilla / Beck, F.-X., Neuhofer, W. -- Osmosensing and signaling in the regulation of liver function / Schliess, F., Hussinger, D. -- Cell volume and peptide hormone secretion / Strbÿk, V. -- Volume changes in neurons : hyperexcitability and neuronal death / Pasantes-Morales, H., Tuz, K. -- Pathophysiology of red cell volume / Browning, J.A., Ellory, J.C., Gibson, J.S |
| Summary |
It is essential for the survival of cells to maintain their volume within certain limits: Profound alterations interfere with the integrity of the cell membrane and the cytoskeletal architecture. Cells use various methods to adjust osmotic pressure gradients which in turn govern water movement across cell membranes. The most rapid and efficient means is ion transport across the cell membrane. However, to avoid excessive alterations of intracellular ion concentration, cells additionally employ organic osmolytes for osmoregulation and modify their metabolism, thus generating or disposing osmotically active organic substances. But a given cell uses only part of the cell volume regulatory mechanisms at their disposal: The large repertoire available allows for a selection of those which have the least untoward impact on cell function. The present book is a collection of reviews on the various aspects of cell volume regulation, written by internationally leading experts, and constitutes a valuable addition to the library of those working in the field |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Osmoregulation.
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Cellular control mechanisms.
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Homeostasis.
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Cell Size
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Osmoregulation
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Homeostasis
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Ion Channels -- physiology
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Ion Transport -- physiology
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Signal Transduction -- physiology
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SCIENCE -- Life Sciences -- Biochemistry.
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Cellular control mechanisms
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Homeostasis
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Osmoregulation
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Zellvolumen -- Regulation -- Aufsatzsammlung.
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| Form |
Electronic book
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| Author |
Lang, Florian.
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S. Karger (Firm)
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| ISBN |
9783318013931 |
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3318013935 |
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9781429468381 |
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1429468386 |
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