| Description |
1 online resource (xvi, 400 pages) : illustrations (some color) |
| Series |
Series on advances in bioinformatics and computational biology ; v. 4 |
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Series on advances in bioinformatics and computational biology ; v. 4.
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| Contents |
Committees -- Referees -- Preface -- Keynote Addresses. Exploring the ocean's microbes: sequencing the seven seas / Marvin E. Frazier [and others]. Don't know much about philosophy: the confusion over bio-ontologies / Mark A. Musen -- Invited talks. Biomedical Informatics Research Network (BIRN): building a national collaboratory for bioMedical and brain research / Mark H. Ellisman. Protein network comparative genomics / Trey Ideker. Systems biology in two dimensions: understanding and engineering membranes as dynamical systems / Erik Jakobsson. Bioinformatics at Microsoft Research / Simon Mercer. Movie crunching in biological dynamic imaging / Jean-Christophe Olivo-Marin. Engineering nucleic acid-based molecular sensors for probing and programming cellular systems / Christina D. Smolke. Reactome: a knowledgebase of biological pathways / Lincoln Stein [and others] -- Structural bioinformatics. Effective optimization algorithms for fragment-assembly based protein structure prediction / Kevin W. DeRonne and George Karypis. Transmembrane helix and topology prediction using hierarchical SVM classifiers and an alternating geometric scoring function / Allan Lo [and others]. Protein fold recognition using the gradient boost algorithm / Feng Jiao [and others]. A graph-based automated NMR backbone resonance sequential assignment / Xiang Wan and Guohui Lin. A data-driven, systematic search algorithm for structure determination of denatured or disordered proteins / Lincong Wang and Bruce Randall Donald. Multiple structure alignment by optimal RMSD implies that the average structure is a consensus / Xueyi Wang and Jack Snoeyink. Identification of?-Helices from low resolution protein density maps / Alessandro Dal Palu [and others]. Efficient annotation of non-coding RNA structures including pseudoknots via automated filters / Chunmei Liu [and others]. Thermodynamic matchers: strengthening the significance of RNA folding energies / Thomas Hochsmann, Matthias Hochsmann and Robert Giegerich -- Microarray data analysis and applications. PEM: a general statistical approach for identifying differentially expressed genes in time-course cDNA microarray experiment without replicate / Xu Han, Wing-Kin Sung and Lin Feng. Efficient generalized matrix approximations for biomarker discovery and visualization in gene expression data / Wenyuan Li [and others] -- Computational genomics and genetics. Efficient computation of minimum recombination with genotypes (not haplotypes) / Yufeng Wu and Dan Gusfield. Sorting genomes by translocations and deletions / Xingqin Qi [and others]. Turning repeats to advantage: scaffolding genomic contigs using LTR retrotransposons / Ananth Kalyanaraman, Srinivas Aluru and Patrick S. Schnable. Whole genome composition distance for HIV-1 genotyping / Xiaomeng Wu [and others]. Efficient recursive linking algorithm for computing the likelihood of an order of a large number of generic markers / S. Tewari, S.M. Bhandarkar and J. Arnold. Optimal Imperfect Phylogeny Reconstruction and Haplotyping (IPPH) / Srinath Sridhar [and others]. Toward an algebraic understanding of haplotype inference by pure parsimony / Daniel G. Brown and Ian M. Harrower. Global correlation analysis between redundant probe sets using a large collection of Arabidopsis ATH1 expression profiling data / Xiangqin Cui and Ann Loraine -- Motif sequence identification. Distance-based identification of structure motifs in proteins using constrained frequent subgraph mining / Jun Huan [and others]. An improved Gibbs sampling method for motif discovery via sequence weighting / Xin Chen and Tao Jiang. Detection of cleavage sites for HIV-1 protease in native proteins / Liwen You. A methodology for motif discovery employing iterated cluster re-assignment / Osman Abul, Finn Drabls and Geir Kjetil Sandve -- Biological pathways and systems. Identifying biological pathways via phase decomposition and profile extraction / Yi Zhang and Zhidong Deng. Expectation-maximization algorithms for fuzzy assignment of genes to cellular pathways / Liviu Popescu and Golan Yona. Classification of Drosophila embryonic developmental stage range based on gene expression pattern images / Jieping Ye [and others]. Evolution versus "intelligent design": comparing the topology of protein-protein interaction networks to the internet / Qiaofeng Yang [and others] -- Protein functions and computational proteomics. Cavity-aware motifs reduce false positives in protein function prediction / Brian Y. Chen [and others]. Protein subcellular localization prediction based on compartment-specific biological features / Chia-Yu Su [and others]. Predicting the binding affinity of MHC class II peptides / Fatih Altiparmak, Altuna Akalin and Hakan Ferhatosmanoglu. Codon-based detection of positive selection can be biased by heterogeneous distribution of polar amino acids along protein sequences / Xuhua Xia and Sudhir Kumar. Bayesian data integration: a functional perspective / Curtis Huttenhower and Olga G. Troyanskaya. An iterative algorithm to quantify the factors influencing peptide fragmentation for MS/MS spectrum / Chungong Yu [and others]. Complexity and scoring function of MS/MS Peptide De Novo sequencing / Changjiang Xu and Bin Ma -- Biomedical applications. Expectation-maximization method for reconstructing tumor phylogenies from single-cell data / Gregory Pennington [and others]. Simulating in vitro epithelial morphogenesis in multiple environments / Mark R. Grant, Sean H.J. Kim and C. Anthony Hunt. A combined data mining approach for infrequent events: analyzing HIV mutation changes based on treatment history / Ray S. Lin [and others]. A systems biology case study of ovarian cancer drug resistance / Jake Y. Chen [and others] |
| Summary |
This volume contains about 40 papers covering many of the latest developments in the fast-growing field of bioinformatics. The contributions span a wide range of topics, including computational genomics and genetics, protein function and computational proteomics, the transcriptome, structural bioinformatics, microarray data analysis, motif identification, biological pathways and systems, and biomedical applications. There are also abstracts from the keynote addresses and invited talks. The papers cover not only theoretical aspects of bioinformatics but also delve into the application of new |
| Analysis |
Computational systems |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| Subject |
Bioinformatics -- Congresses
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Computational biology -- Congresses
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Biological systems -- Computer simulation -- Congresses
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Biological systems -- Simulation methods -- Congresses
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COMPUTERS -- Bioinformatics.
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Bioinformatics
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Biological systems -- Computer simulation
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Biological systems -- Simulation methods
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Computational biology
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| Genre/Form |
Conference papers and proceedings
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| Form |
Electronic book
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| Author |
Markstein, Peter.
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Xu, Ying, 1960-
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Hewlett-Packard Company
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Microsoft Research.
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Life Sciences Society.
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| ISBN |
9781860947575 |
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1860947573 |
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1281867373 |
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9781281867377 |
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9786611867379 |
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6611867376 |
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