| Description |
1 online resource (x, 174 pages) : illustrations (some color) |
| Series |
Current topics in microbiology and immunology, 0070-217X ; v. 348 |
|
Current topics in microbiology and immunology ; 348.
|
| Contents |
Hydrogen-bonded synthetic mimics of protein secondary structure as disruptors of protein-protein interactions / M.J. Adler, A.G. Jamieson and A.D. Hamilton -- Small-molecule inhibitors of IL-2/IL-2R: Lessons learned and applied / C.G. Wilson and M.R. Arkin -- Small molecule inhibitors of the human papillomavirus E1-E2 interaction / P.W. White, A.-M. Faucher and N. Goudreau -- Design of small-molecule Smac mimetics as IAP antagonists / S. Wang -- Small-molecule inhibitors reveal a new function for Bcl-2 as a proangiogenic signaling molecule / B.D. Zeitlin and J.E. Nör -- Small-molecule modulators of c-Myc/Max and Max/Max interactions / T. Berg -- Small-molecule inhibitors of the p53-MDM2 interaction / B.T. Vu and L. Vassilev |
| Summary |
In this volume, the editors have collected the knowledgeable insights of a number of leaders in this field - researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions. These researchers describe their unique approaches, and share experiences, results, thoughts, and opinions. The content of the articles is rich, and in terms of scope ranges from generalized approaches to specific case studies. There are various focal points, including methodologies and the molecules themselves. Ultimately, there are numerous lessons to be taken away fro |
| Analysis |
biomedische wetenschappen |
|
biomedicine |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Protein-protein interactions.
|
|
Enzyme inhibitors.
|
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Drugs -- Design.
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Drug Design
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Protein Binding -- drug effects
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Small Molecule Libraries
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Enzyme Inhibitors
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SCIENCE -- Life Sciences -- Biochemistry.
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Drugs -- Design
|
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Enzyme inhibitors
|
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Protein-protein interactions
|
| Form |
Electronic book
|
| Author |
Vassilev, Lyubomir
|
|
Fry, David
|
| ISBN |
9783642170836 |
|
3642170838 |
|
364217082X |
|
9783642170829 |
|
