| Description |
1 online resource (2 volumes) |
| Contents |
Frontmatter -- Color Plates -- Human Immunodeficiency Virus. Discovery and Development of Atazanavir / Awny Farajallah, R Todd Bunch, Nicholas A Meanwell -- Discovery and Development of PL-100, A Novel HIV-1 Protease Inhibitor / Jinzi J Wu, Joseph Musto -- Darunavir (Prezista, TMC114): From Bench to Clinic, Improving Treatment Options for HIV-Infected Patients / Marie-Pierre de B̌thune, Vanitha Sekar, Sabrina Spinosa-Guzman, Marc Vanstockem, Sandra De Meyer, Piet Wigerinck, Eric Lefebvre -- Discovery and Development of Tipranavir / Karen R Romines -- TMC278 (Rilpivirine): A Next-Generation NNRTI in Phase III Clinical Development for Treatment-Naive Patients / Jerome Guillemont, Katia Boven, Herta Crauwels, Marie-Pierre de B̌thune -- Etravirine: From TMC125 to Intelence: A Treatment Paradigm Shift for HIV-Infected Patients / Koen Andries, Ann Debunne, Thomas N Kakuda, Michael Kukla, Ruud Leemans, Johan Vingerhoets, Brian Woodfall, Marie-Pierre de B̌thune -- Discovery and Development of Tenofovir Disoproxil Fumarate / Erik De Clercq -- Discovery and Development of Apricitabine / Susan Cox, John Deadman, Justine Southby, Jonathan Coates -- Discovery and Development of Maraviroc and PF-232798: CCR5 Antagonists for the Treatment of HIV-1 Infection / Patrick Dorr, Paul Stupple -- Discovery of the CCR5 Antagonist Vicriviroc (Sch 417690/Sch-D) for the Treatment of HIV-1 Infection / Jayaram R Tagat, Julie M Strizki, Lisa M Dunkle -- Discovery and Development of HIV-1 Entry Inhibitors That Target gp120 / John F Kadow, John Bender, Alicia Regueiro-Ren, Yasutsugu Ueda, Tao Wang, Kap-Sun Yeung, Nicholas A Meanwell -- Discovery of MK-0536: A Potential Second-Generation HIV-1 Integrase Strand Transfer Inhibitor with a High Genetic Barrier to Mutation / Melissa S Egbertson, John S Wai, Mark Cameron, R Scott Hoerrner -- Discovery and Development of HIV Integrase Inhibitor Raltegravir / Vincenzo Summa, Paola Pace -- Elvitegravir: A Novel Monoketo Acid HIV-1 Integrase Strand Transfer Inhibitor / Hisashi Shinkai, Masanori Sato, Yuji Matsuzaki -- Hepatitis C Virus. Discovery and Development of Telaprevir / Anne-Laure Grillot, Luc J Farmer, B Govinda Rao, William P Taylor, Ilan S Weisberg, Ira M Jacobson, Robert B Perni, Ann D Kwong -- Discovery and Development of BILN 2061 and Follow-Up BI 201335 / Montse Llin̉s-Brunet, Peter W White -- Intervention of Hepatitis C Replication through NS3-4A, the Protease Inhibitor Boceprevir / Srikanth Venkatraman, F George Njoroge -- Discovery and Development of the HCV NS3/4A Protease Inhibitor Danoprevir (ITMN-191/RG7227) / Scott D Seiwert, Karl Kossen, Lin Pan, Jyanwei Liu, Brad O Buckman -- Discovery and Development of the HCV Protease Inhibitor TMC435 / Pierre Raboisson, Gregory Fanning, Herman de Kock, Asa Rosenquist, Rene Verloes, Kenneth Simmen -- Discovery and Clinical Evaluation of the Nucleoside Analog Balapiravir (R1626) for the Treatment of HCV Infection / Klaus Klumpp, David B Smith -- Discovery and Development of PSI-6130/RG7128 / Phillip A Furman, Michael J Otto, Michael J Sofia -- Discovery of Cyclophilin Inhibitor NIM811 as a Novel Therapeutic Agent for HCV / Kai Lin -- HCV Viral Entry Inhibitors / Flossie Wong-Staal, Guohong Liu, Jeffrey McKelvy -- Respiratory Syncytial Virus Inhibitors. Discovery of the RSV Inhibitor TMC353121 / Jean-Fraṅois Bonfanti, Gabriela Ispas, Frans Van Velsen, Wieslawa Olszewska, Tom Gevers, Dirk Roymans -- Discovery and Development of Orally Active RSV Fusion Inhibitors / Nicholas A Meanwell, Christopher W Cianci, Mark R Krystal -- Discovery and Development of RSV604 / Joanna Chapman, Stuart Cockerill -- Influenza, Hepatitis B, and Cytomegalovirus Inhibitors. Discovery and Development of Influenza Virus Sialidase Inhibitor Relenza / Robin Thomson, Mark von Itzstein -- Discovery and Development of Entecavir / Richard Wilber, Bruce Kreter, Marc Bifano, Stephanie Danetz, Lois Lehman-McKeeman, Daniel J Tenney, Nicholas Meanwell, Robert Zahler, Helena Brett-Smith -- Benzimidazole Ribonucleosides: Novel Drug Candidates for the Prevention and Treatment of Cytomegalovirus Diseases / Karen K Biron, Kristjan S Gudmundsson, John C Drach -- Index |
| Notes |
Print version record |
| Subject |
Antibiotics.
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Anti-infective agents.
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Anti-Infective Agents
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MEDICAL -- Pharmacology.
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Anti-infective agents
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Antibiotics
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| Form |
Electronic book
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| Author |
Grayson, M. Lindsay.
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Kucers, A.
Use of antibiotics
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| ISBN |
9781444128666 |
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1444128663 |
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