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Title Nevogenesis : mechanisms and clinical implications of nevus development / Ashfaq A. Marghoob, editor
Published Heidelberg ; New York : Springer, ©2012

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Description 1 online resource
Contents Nevogenesis: Changing Theories / Mark E. Burnett, Ashfaq A. Marghoob, Alon Scope -- Classifying Melanocytic Nevi / Iris Zalaudek, Caterina Longo, Cinzia Ricci -- Evolution of Nevi / Harald Kittler -- The Dual Pathway of Nevogenesis / Iris Zalaudek, Alon Scope, Giuseppe Argenziano -- Confocal Microscopy: Improving Our Understanding of Nevogenesis / Barbara De Pace, Barbara Ferrari, Giovanni Pellacani, Barbara Predieri -- Nevi in Children and Adults: Dermoscopic Patterns and the Development of New Nevi / Tracey Liebman, Natalia Jaimes Lopez, Stephen W. Dusza -- Etiology of Congenital Melanocytic Nevi and Related Conditions / Miguel Reyes-Múgica, Mark Beckwith, Heather C. Etchevers -- Molecular Nevogenesis: An Update / Andrew L. Ross, Margaret I. Sanchez, James M. Grichnik -- Nevogenesis: A Benign Metastatic Process?: An Update / Andrew L. Ross, Margaret I. Sanchez, James M. Grichnik -- Nevus Senescence: An Update / Andrew L. Ross, Margaret I. Sanchez, James M. Grichnik -- Genes and Nevogenesis / Stephen W. Dusza, Mark E. Burnett -- Malignant Transformation of Melanocytic Nevi / Alexander Marzuka-Alcalá, Hensin Tsao -- Disappearance of Melanocytic Nevi / Vitaly Terushkin, Ashfaq A. Marghoob, Alon Scope
Summary Paul Gerson Unna's "Abtropfung" theory that nevi develop through migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the "Hochsteigerung" theory postulated the reverse pattern of migration based on newly acquired observations from histopathology and studies of embryogenesis. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of the aforementioned theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis
Bibliography Includes bibliographical references and index
Notes Online resource; title from digital title page (viewed November 14, 2012)
Subject Mole (Dermatology)
Melanocytes.
Birthmarks.
Nevus -- physiopathology
Skin Neoplasms -- physiopathology
Nevus
Melanocytes
HEALTH & FITNESS -- Diseases -- Skin.
MEDICAL -- Dermatology.
Médecine.
Birthmarks
Melanocytes
Mole (Dermatology)
Form Electronic book
Author Marghoob, Ashfaq A.
ISBN 9783642283970
3642283977
3642283969
9783642283963