AUTISM: NEURAL BASIS AND TREATMENT POSSIBILITIES; Contents; Participants; Introduction: autism -- the challenges ahead; Epidemiology and early identification of autism: research challenges and opportunities; Implications of the broader phenotype for concepts of autism; Strategies for autism candidate gene analysis; How might genetic mechanisms operate in autism?; X-linked genes and the neural basis of social cognition; General discussion I; The neuropathology of the autism spectrum disorders: what have we learned?; Microbiology and immunology of autism spectrum disorders
Summary
This groundbreaking book brings together contributions by leading scientists from different fields to provide a balanced view of the spectrum of current studies on autism. Four main areas of research are covered. Twin and family data indicate that the heritability of the underlying liability to autism exceeds 90%. This probably involves interactions among a relatively small number of susceptibility genes, an hypothesis that is examined in detail. New techniques are now available for examining the neurobiology of autism. The book contains results from imaging studies showing the contributions of