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Title Biodiversity : new leads for the pharmaceutical and agrochemical industries / edited by Stephen K. Wrigley [and others]
Published Cambridge : Royal Society of Chemistry, ©2000

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Description 1 online resource (vi, 313 pages) : illustrations
Series Special publication ; no. 257
Special publication (Royal Society of Chemistry (Great Britain)) ; no. 257.
Contents Microbial natural products : a past with a future -- New concepts and approaches to biodiversity -- Nature products drug discovery at the National Cancer Institute : past achievements and new directions for the new millennium -- Secondary metabolites as a vital source of animal health products -- The relationship between natural products and synthetic chemistry in the discovery process -- Natural products vs. combinatorials : a case study -- Mushrooms, microbes and medicines -- Signal transduction inhibitors from microorganisms -- Novel inhibitors of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579 -- Marine organisms as a source of novel lead structures for drug development -- The anticancer dolastatins as cyanobacterial metabolites -- A Cu² selective marine metabolite -- Water soluble bioactive alkaloids -- "Lessons from nature" : can ecology provide new leads in the search for novel bioactive chemicals from tropical rainforests? -- Brazilian biodiversity : a source of phytomedicines, natural drugs and leads for the pharmaceutical and agrochemical industries -- A modern perspective to the traditional use of plants in the highlands of Scotland -- In vivo and in vitro biosynthetic studies : Understanding and exploiting natural pathways -- Fused ring aromatic polyketides are formed by different cyclisation pathways in fungi and streptomycetes -- The strobilurin fungicides : from mushroom to molecule to market -- A synthesis of (+)prelog-Djerassi lactonic acid -- N-([alpha]-aminoacyl)-5'-O-sulfamoyladenosines : natural product based inhibitors of amino acyl tRNA synthetases
Summary This product is not available separately, it is only sold as part of a set. There are 750 products in the set and these are all sold as one entity. The continuing quest for new drugs and agrochemicals has seen researchers looking to the natural world for potential products. Plants and microorganisms have long been investigated as sources of new lead compounds, but the scope of this book has been widened to include substances derived from marine organisms. Advances in genetic engineering, high throughput screening and structure elucidation have also opened up further avenues for exploration. Competitive pressure from the field of combinatorial chemistry has expedited new approaches to natural product analysis and stimulated debate on the industrial utilization of natural products. Biodiversity: New Leads for the Pharmaceutical and Agrochemical Industries reviews and discusses aspects of modern natural products research. The central theme of many articles is the sustainable use of global biodiversity. Microbial, plant and marine products are presented as the sources of new drugs, including antifungal products, antibiotics, anticancer agents and animal health products. There is also coverage of the biosynthesis of polyketides and the chemical synthesis of natural products and their derivatives. A unique blend of industrial and academic perspectives on the importance of biodiversity and natural products, this book will prove an important source of state-of-the-art information for researchers, teachers and graduates in the chemical and biological sciences
Notes "Volume is based on the proceedings of the International conference entitled Biodiversity : a source of new leads for the Pharmaceutical and Agrochemical industries held at the University of St. Andrews 5-8 September, 1999"--Page iii
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Biodiversity.
Sustainable development.
Biotechnology.
Genetic engineering.
Bioengineering.
sustainable development.
bioengineering.
Chemistry.
NATURE -- Animals -- Wildlife.
SCIENCE -- Microscopes & Microscopy.
Science.
Bioengineering
Biodiversity
Biotechnology
Genetic engineering
Sustainable development
Form Electronic book
Author Wrigley, Stephen.
Biodiversity: A Source of New Leads for the Pharmaceutical and Agochemical Industries (1999 : University of St. Andrews)
ISBN 9781847550231
1847550231