Limit search to available items
Book Cover
E-book
Author Shen, Shiyi.

Title Theory and mathematical methods in bioinformatics / Shiyi Shen, Jack A. Tuszynski
Published Berlin : Springer, ©2008

Copies

Description 1 online resource (xvi, 445 pages) : illustrations
Series Biological and medical physics, biomedical engineering, 1618-7210
Biological and medical physics, biomedical engineering. 1618-7210
Contents pt. I. Mutations and Alignments. Introduction -- Stochastic Models of Mutations and Structural Analysis -- Modulus Structure Theory -- Super Pairwise Alignment -- Multiple Sequence Alignment -- Network Structures of Multiple Sequences Induced by Mutation -- Alignment Space -- pt. II. Protein Configuration Analysis. Background Information Concerning the Properties of Proteins -- Informational and Statistical Iterative Analysis of Protein Secondary Structure Prediction -- Three-Dimensional Structure Analysis of the Protein Backbone and Side Chains -- Alignment of Primary and Three-Dimensional Structures of Proteins -- Depth Analysis of Protein Spatial Structure -- Analysis of the Morphological Features of Protein Spatial Structure -- Semantic Analysis for Protein Primary Structure
Summary "This monograph addresses, in a systematic and pedagogical manner, the mathematical methods and the algorithms required to deal with the molecularly based problems of bioinformatics. The book will be useful to students, research scientists and practitioners of bioinformatics and related fields, especially those who are interested in the underlying mathematical methods and theory. Among the methods presented in the book, prominent attention is given to pair-wise and multiple sequence alignment algorithms, stochastic models of mutations, modulus structure theory and protein configuration analysis. Strong links to the molecular structures of proteins, DNA and other biomolecules and their analyses are developed. In particular, for proteins an in-depth exposition of secondary structure prediction methods should be a valuable tool in both molecular biology and in applications to rational drug design. The book can also be used as a textbook and for this reason most of the chapters include exercises and problems at the level of a graduate program in bioinformatics."--Jacket
Analysis bioinformatics
biofysica
biophysics
populatiegenetica
population genetics
populatiedynamica
population dynamics
biomedische wetenschappen
biomedicine
humane genetica
human genetics
eiwitexpressieanalyse
proteomics
Bioinformatics (General)
Bioinformatica (algemeen)
Bibliography Includes bibliographical references (pages 433-439) and index
Notes English
Print version record
In Springer eBooks
Subject Bioinformatics -- Mathematics
Mathematics -- Problems, exercises, etc.
Mathematical models.
Computational Biology -- methods
Models, Theoretical
mathematical models.
COMPUTERS -- Bioinformatics.
Mathematics.
Computational Biology -- methods.
Models, Theoretical.
Bioinformatics -- Mathematics.
Biomédecine.
Sciences de la vie.
Mathematical models
Mathematics
Genre/Form exercise books.
Problems and exercises
Problems and exercises.
Problèmes et exercices.
Form Electronic book
Author Tuszynski, J. A.
LC no. 2007939206
ISBN 9783540748915
3540748911