| Description |
xvi, 501 pages, 6 unnumbered pages of plates : illustrations (some color) ; 25 cm |
| Series |
Springer Nature Book Archives Millennium (2000-2004)
|
| Contents |
Machine derived contents note: From the contents: Preface.- Origins and Directions of Human Cytogenetics.- The Mitotic Cell Cycle and Chromosome Reproduction.- General Features of Mitotic Chromosomes.- The Chemistry and Packaging of Chromosomes.- Chromosome Bands.- Molecular Correlates of Chromosome Bands.- In situ Hybridization.- Somatic Cell Hybridization in Cytogenetic Analysis.- Main Features of Meiosis.- Details of Meiosis.- Meiotic Abnormalities: Abnormal Numbers of Chromosomes.- Abnormal Phenotypes due to Autosomal Aneuploidy.- Phenotypic Effects of Sex Chromosome Imbalance.- Sex Determination and the Y-chromosome.- The X Chromosome, Dosage Compensation, and X-inactivation.- Euploid Chromosome Aberrations, Uniparental Dsomy, and Imprinting.- Chromosome Changes During Cell Differentiation.- Chromosomal Structural Aberrations.- Abnormal Phenotypes Due to Autosomal Duplications and Deletions.- Structural Aberrations Involving Two or More Chromosomes.- Clinical Importance of Translocations and Inversions.- Chromosome Instability Syndromes.- Sister Chromatid Exchanges and Mitotic Crossing-Over.- Genome Instability and Multistep Carcinogenesis.- Chromosomes and Cancer. And much more. |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Human chromosome abnormalities.
|
|
Human chromosomes.
|
|
Human cytogenetics.
|
| Author |
Therman, Eeva.
|
| LC no. |
00044007 |
| ISBN |
0387950311 |
|
038795046X |
|
