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Book Cover
Author Kapur, Shitij.

Title Dopamine in the pathophysiology and treatment of schizophrenia : new findings / edited by Shitij Kapur, Yves Lecrubier
Published London ; New York : Martin Dunitz ; Independence, KY : Distributed in the USA by Fulfilment Center, Taylor & Francis, 2003


Description 1 online resource (xi, 259 pages) : color illustrations
Contents ""Book Cover""; ""Half-Title""; ""Title""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""chapter 1 Historical aspects and future directions ""; "" chapter 2 Evidence from brain imaging studies for dopaminergic alterations in schizophrenia""; ""Chapter 3 Modulation of dopamine D2 receptors as a basis of antipsychotic effect ""; "" Chapter 4 Amisulpride as a model: clinical effects of a pure dopaminergic agent ""; "" chapter 5 A meta-analysis of studies with the atypical antipsychotic amisulpride ""
""Chapter 6 Evidence from brain imaging for regional monoaminergic specificity in schizophrenia""""chapter 7 Dopamine, the prefrontal cortex, and a genetic mechanism of schizophrenia ""; ""chapter 8 Models of schizophrenia: from neuroplasticity and dopamine to psychopathology and clinical management ""; ""chapter 9 Multiple neurotransmitters involved in antipsychotic drug action ""; ""chapter 10 Dopaminergic and glutamatergic influences in the systems biology of schizophrenia ""; ""chapter 11 Pharmacogenomics of antipsychotic drugs ""
Summary Covering the latest advances in the field, Dopamine in the Treatment of Schizophrenia, Second Edition provides a detailed explanation of the etiology and clinical presentation of the disease, especially as related to the dopamine system. Written by an international team of experts, the text identifies genetic polymorphisms that affect dopaminergic neurotransmission and their possible impact on familial forms of schizophrenia. It also explores the neurophysiological and neurochemical studies of dopaminergic function and the integration of dopamine-containing neurons with other transmitter systems. It reviews imaging studies and their contribution to our understanding of the pathophysiology of schizophrenia and the mechanism of action of antipsychotics. Finally, the book puts the role of dopamine in the context of other brain systems and highlights the many unmet needs of patients, despite best current treatments
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Dopamine.
Schizophrenia -- Pathophysiology
Dopamine -- Pathophysiology
Schizophrenia -- Chemotherapy.
Schizophrenia -- drug therapy
Schizophrenia -- physiopathology
Dopamine -- therapeutic use
PSYCHOLOGY -- Psychopathology -- Schizophrenia.
Schizophrenia -- Chemotherapy
Schizophrenia -- Pathophysiology
Form Electronic book
Author Lecrubier, Yves.
ISBN 0203427343