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Title Nitric oxide : biology and pathobiology / Louis J. Ignarro
Edition 1st ed
Published San Diego : Academic Press, ©2000


Description 1 online resource (xvii, 1003 pages, [10] pages of color plates) : illustrations
Contents Front Cover; Nitric Oxide Biology and Pathobiology; Copyright Page; Contents; Contributors; Preface; Section I: Overview of Basic Principles; Section II: Principles of Biology; Section III: Principles of Pathobiology; Index
Summary Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Key Features * Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide * Authored by world experts on nitric oxide * Includes an overview of basic principles of biology and chemical biology * Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense
Analysis stikstofoxide
nitric oxide
signal transduction
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Nitric oxide -- Physiological effect
Nitric oxide -- Pathophysiology
Nitric Oxide -- physiology
Nitric Oxide -- therapeutic use
SCIENCE -- Life Sciences -- Biochemistry.
Nitric oxide -- Pathophysiology.
Nitric oxide -- Physiological effect.
Pathologische fysiologie.
Form Electronic book
Author Ignarro, Louis J.
ISBN 9780123704207