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Title Development of oral cancer : risk factors and prevention strategies / Ala-Eddin Al Moustafa, editor
Published Cham : Springer, 2017


Description 1 online resource (219 pages)
Contents Preface; Contents; 1: Human Oral Cancer (Epidemiology and Characteristic); 1.1 Introduction; 1.2 Oral Cancer Epidemiology; 1.2.1 Incidence and Mortality; 1.2.2 Age and Gender; 1.2.3 Site; 1.2.4 Trends and Variations; 1.2.5 2035 Projection; 1.2.6 Survival; 1.3 Clinical Characteristics; 1.4 Early Detection and Prevention of Oral Cancer; 1.4.1 Primary Prevention; 1.4.2 Secondary Prevention (Screening); References; 2: Novel Developments in the Molecular Genetic Basis of Oral Squamous Cell Carcinoma (OSCC); 2.1 Introduction; 2.2 Transcriptional Factors
2.3 Tumor Suppressor Genes or Anti-oncogenes2.4 Proto-oncogenes and Oncogenes; 2.5 Gene Expression; 2.6 Cell Surface Receptors; 2.7 Epigenetic Changes; 2.8 Chromosomal Instability and Copy Number Variation; 2.9 mtDNA Mutation; 2.10 Telomeres and Telomerase; 2.11 Microsatellite Instability and Alteration; 2.12 Noncoding RNA; 2.13 MicroRNA (miRNA); 2.14 Long Noncoding RNAs (lncRNAs); References; 3: Oral Cancer: After the Completion of the Human Genome Project; 3.1 Gene Profiling: (A Personal Journey); 3.2 Drug Design to Shut Off Bad Genes; References; 4: Smoking and Oral Cancer
4.1 Introduction4.2 History of Tobacco Usage; 4.3 Cigarettes and Other Forms of Tobacco Preparations; 4.4 Composition and Carcinogenesis; 4.5 Effects on Oral Health; 4.5.1 Oral Hygiene and Aesthetics; 4.5.2 Oral Mucosal Diseases: Nonmalignant; 4.5.3 Oral Premalignant Disorders; 4.5.4 Oral Cancer; 4.6 Prevention Strategies; References; 5: Alcohol and Oral Cancer; 5.1 Introduction; 5.2 Alcohol and Oral Cancer: Epidemiological Evidence; 5.3 Alcoholic Beverages and Weekly Consumption; 5.4 Topical Effects; 5.5 Systemic Effects; 5.6 Synergistic Effects with Tobacco Use
5.7 Alcohol-Related Oral Carcinogenesis5.8 Alcohol-Containing Mouthwashes and Oral Cancer; 5.9 Prevention; References; 6: High-Risk Human Papillomaviruses and Epstein-Barr Virus Presence and Crosstalk in Human Oral Carcinogenesis; 6.1 Introduction; 6.2 High-Risk Human Papillomaviruses (HPVs) in Human Cancer; 6.3 Epstein-Barr Virus (EBV) in Human Cancer; 6.4 High Risk of HPVs and EBV in Human Oral Cancer; 6.5 Conclusion and Perspectives; References; 7: Oral Cancer: Epidemiology and Infections (Bacterial and Fungal) Global Incidence; 7.1 Introduction
7.2 Worldwide Incidence of Oral Cancer by Gender, Age and Primary Site7.3 Oral Cancer Mortality and Survival; 7.4 Bacteria and Cancer; 7.4.1 Anatomy; 7.4.2 Clinical Presentation; 7.4.3 Pathology; 7.4.4 Virus; HPV; Human Immunodeficiency Virus; Herpes Simplex Virus; 7.4.5 Dental Considerations; Hygiene; Dentures; Oral Cancer in the UAE; References; 8: Oral Cancer and Chewing Habits; 8.1 Introduction; 8.2 Oral Cancer Statistics: Global Incidence, Prevalence, Mortality, and Survival
Summary This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. Some of the discussed risk factors are well known, including smoking, alcohol, betel quid chewing, and oncoviruses such as high-risk human papillomaviruses and Epstein-Barr virus; however, careful attention is also paid to less widely recognized factors, such as Qat chewing and yerba Mate consumption. The book concludes by describing and evaluating the most important strategies currently available for the prevention of oral carcinogenesis in humans. In presenting the most up-todate research and knowledge on these topics, this book will serve as a valuable source of up-to-date information for oncologists, cancer scientists, and medical students
Notes 8.3 Epidemiology in Asia: A Region with High Burden of Oral Cancer
Bibliography Includes bibliographical references at the end of each chapters
Notes Print version record
Subject Mouth -- Cancer -- Etiology
Mouth Neoplasms -- etiology
Mouth Neoplasms -- prevention & control
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Mouth -- Cancer -- Etiology
Genre/Form Electronic book
Form Electronic book
Author Al Moustafa, Ala-Eddin
ISBN 9783319480541