| Description |
1 online resource (xiii, 199 pages) : illustrations |
| Series |
Current topics in microbiology and immunology, 0070-217X ; 324 |
|
Current topics in microbiology and immunology ; 324. 0070-217X
|
| Contents |
Basic Concept of Development and Practical Application of Animal Models for Human Diseases -- Humanized SCID Mouse Models for Biomedical Research -- NOD/Shi-scid IL2r?null (NOG) Mice More Appropriate for Humanized Mouse Models -- Humanizing Bone Marrow in Immune-Deficient Mice -- The Differentiative and Regenerative Properties of Human Hematopoietic Stem/Progenitor cells in NOD-SCID/IL2r?null Mice -- Antigen-Specific Antibody Production of Human B Cells in NOG Mice Reconstituted with the Human Immune System -- Humanized Immune System (HIS) Mice as a Tool to Study Human NK Cell Development -- Human T Cell Development and HIV Infection in Human Hemato-Lymphoid System Mice -- Humanized Mice for Human Retrovirus Infection -- Functional and Phenotypic Characterization of the Humanized BLT Mouse Model -- Novel Metastasis Models of Human Cancer in NOG Mice -- In Vivo Imaging in Humanized Mice |
| Summary |
Annotation In a humanized mouse transplanted human tissues and cells show the same biological function as they do in the human body. It has become possible to study the pathophysiology and treatment of human diseases in mice with excellent reproducibility, a remarkable breakthrough. Unsurprisingly, the humanized mouse is proving to be one of the most powerful tools in basic and clinical research |
| Analysis |
Humanized mice |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| In |
Springer eBooks |
| Subject |
Mice as laboratory animals.
|
|
Transgenic mice.
|
|
Mice, Transgenic
|
|
Models, Animal
|
|
SCIENCE -- Life Sciences -- Zoology -- Mammals.
|
|
NATURE -- Animals -- Mammals.
|
|
Models, Animal.
|
|
Mice as laboratory animals.
|
|
Mice, Transgenic.
|
|
Biomédecine.
|
|
Sciences de la vie.
|
|
Transgenic mice
|
|
Mice as laboratory animals
|
| Form |
Electronic book
|
| Author |
Nomura, Tatsuji, 1922-2013, editor.
|
|
Watanabe, Takeshi, 1940- editor.
|
|
Habu, Sonoko, editor.
|
| LC no. |
2007940882 |
| ISBN |
9783540756477 |
|
3540756477 |
|
9783540756460 |
|
3540756469 |
|
1281241903 |
|
9781281241900 |
|
9786611241902 |
|
6611241906 |
|
