| Description |
1 online resource (xiv, 244 pages, [1] pages) : illustrations (some color) |
| Series |
Wiley series in drug discovery and development |
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Wiley series in drug discovery and development.
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| Contents |
In vitro evaluation of metabolic drug-drug interactions: concepts and practice / Albert P. Li -- In vitro approaches to anticipating clinical drug interactions / Laurie P. Volak, David J. Greenblatt, Lisa L. von Moltke -- Inhibition of drug metabolizing enzymes and drug-drug interactions in drug discovery and development / R. Scott Obach -- Mechanism-based CYP inhibition: enzyme kinetics, assays, and prediction of human drug-drug interactions / Magang Shou -- Genomic approaches to drug-drug interactions / Yi Yang, Jeffrey F. Waring -- Transporters and drug interactions / Yoshihisa Shitara, Toshiharu Horie, and Yuichi Sugiyama -- Transporter-mediated drug interactions: molecular mechanisms and clinical implications / Jiunn H. Lin -- Recent case studies of clinically significant drug-drug interactions and the limits of in vitro prediction methodology / R.H. Levy, I. Ragueneau-Majlessi, C. Collins -- US regulatory perspective: drug-drug interactions / John Strong and Shiew-Mei Huang -- Herbal drug interactions: a Canadian perspective / Brian C. Foster |
| Summary |
Drug-Drug Interactions in Pharmaceutical Development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Drug interactions.
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Drug development.
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Pharmaceutical chemistry.
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Drug Interactions
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Chemistry, Pharmaceutical
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Drug Combinations
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MEDICAL -- Pharmacology.
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Pharmaceutical chemistry.
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Drug development.
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Drug interactions.
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Arzneimittelentwicklung
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Arzneimittelwechselwirkung
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| Form |
Electronic book
|
| Author |
Li, A. P.
|
| LC no. |
2007015878 |
| ISBN |
9780470187913 |
|
0470187913 |
|
9780470187920 |
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0470187921 |
|
1282022067 |
|
9781282022065 |
|
9786612022067 |
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661202206X |
|
