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Author Williams, Andrew, 1937-

Title Free energy relationships in organic and bio-organic chemistry / Andrew Williams
Published Cambridge : Royal Society of Chemistry, ©2003


Description 1 online resource (xi, 297 pages) : illustrations
Contents Free energy relationships -- The equations -- Effective charge -- Multiple pathways to the reaction centre -- Coupling between bonds in transition structures of displacement reactions -- Anomalies, special cases and non-linearity -- Applications
Summary Introducing the application of free energy correlations to elucidating the mechanisms of organic and bio-organic reactions, this book provides a new and illuminating way of approaching a potentially complex topic. The idea of how free energy correlations derive from polar substituent change is introduced, and common pitfalls encountered in the application of free energy relationships are described, along with the use of these anomalies in mechanistic studies. The concept of effective charge is described in detail, with examples of its application. Throughout, worked answers are provided for the problems posed. Databases of parameters, an extensive bibliography and comprehensive lists of further reading are also included. The text provides an invaluable source of information to senior undergraduates, postgraduates and to industrial researchers with an interest in mechanistic studies. It is the first such book in more than thirty years
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Linear free energy relationship.
SCIENCE -- Chemistry -- Organic.
Linear free energy relationship
Vrije energie.
Form Electronic book
ISBN 9781847550927