An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Multiple sclerosis -- Diagnosis -- Popular works : Navigating life with multiple sclerosis / Kathleen Costello, MS, ANP-BC, MSCN (Associate Vice-President, National Multiple Sclerosis Society Nurse Practitioner, the Johns Hopkins Multiple Sclerosis Center, Baltimore, MD), Ben W. Thrower, MD (Medical Director, Andrew C. Carlos Multiple Sclerosis Institute at Shepherd Center, Atlanta, GA), Barbara S. Giesser, MD (Clinical Director, UCLA Multiple Sclerosis Program, David Geffen UCLA School of Medicine, Los Angeles, CA)
2015
1
17
Multiple sclerosis -- Dictionaries. : Dictionary of multiple sclerosis / editor-in-chief, Lance D. Blumhardt ; associate editor, Xia Lin ; section editors, C.S. Constantinescu [and others]
Multiple sclerosis -- Imaging : Imaging and imagining illness : becoming whole in a broken body / edited by Devan Stahl ; foreword by Rosemarie Garland-Thomson
Multiple sclerosis in children. : Pediatric demyelinating diseases of the central nervous system and their mimics : a case-based clinical guide / Emmanuelle Waubant, Timothy E. Lotze, editors
