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Small Interfering RNA -- See RNA, Small Interfering


Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions
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2 Small interfering RNA.   24
3 Small interfering RNA -- Diagnostic use -- Periodicals : MicroRNA diagnostics and therapeutics  2013 1
4 Small interfering RNA -- Handbooks, manuals, etc.   2
5 Small interfering RNA -- Laboratory manuals.   2
6 Small interfering RNA -- Physiology. : RNA silencing : methods and protocols / edited by Gordon Carmichael  2005 1
7 Small interfering RNA -- Research : MicroRNA cancer regulation : advanced concepts, bioinformatics and systems biology tools / edited by Ulf Schmitz, Olaf Wolkenhauer, Julio Vera  2013 1
8 Small interfering RNA -- Therapeutic use   7
9 Small interfering RNA -- Therapeutic use -- Periodicals : MicroRNA diagnostics and therapeutics  2013 1
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