Oral Cancer Overview: The Significance of Metastasis and Surgical Management of the Neck -- The Role of Diagnostic Imaging in Identifying Cervical Metastases in Oral Cavity Cancer -- Sentinel Node Biopsy in Oral Cancer -- Prediction of Nodal Metastases from Genomic Analyses of the Primary Oral Cavity Tumor -- The Role of High Throughput Molecular Analysis of Biofluids and Tumors in Patients with Oral Cancer -- Adjuvant Therapy for Patients with Oral Cavity Cancer -- Animal Models of Oral Cancer Metastases -- TGFb Signaling in Head and Neck Cancer Development and Metastases -- Growth Factor Receptor Signaling and Metastasis of Oral Cancer -- Nuclear Transcription Factors and Signaling Pathways in Oral Cancer Metastasis -- Wnt/ß-catenin Signaling and Oral Cancer Metastasis -- Role of Tumor Stromal Interactions and Proteases in Oral Cancer Metastasis -- Chemokines and their Receptors in Oral Cancer Metastasis -- Hypoxia, Angiogenesis and Oral Cancer Metastasis -- Cancer Stem Cells and Oral Cancer Metastasis
Summary
Squamous cell carcinoma of the oral cavity (SCCOC) is one of the most prevalent tumors of the head and neck region. This book summarizes the status of investigations into SCCOC metastases and potential of these studies to impact basic research investigators and clinicians confronting SCCOC