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Book Cover
Author Lappin, Graham, PhD.

Title Radiotracers in drug development / Graham Lappin, Simon Temple
Published Boca Raton : CRC/Taylor & Francis, 2006


Description 1 online resource (300 pages, 5 unnumbered pages of plates) : illustrations (some color)
Contents Radiotracers and drug registration -- Radioactivity and radiotracers -- The study of drug metabolism using radiotracers -- DNA binding, isotope dilution and other uses of radiotracers -- Quantitative whole-body autoradiography (QWBA) -- Scintillation counting -- Statistics in liquid scintillation counting -- Instrumentation for detection of radioactivity -- Sample preparation for liquid scintillation counting -- Biomedical accelerator mass spectrometry -- Positron emission tomography -- Gamma scintigraphy and SPECT
Summary This book presents up-to-date information on the theory and practice of new technologies. It presents classical radioactive measurement methods and principles of radioactive decay as a foundation for understanding the latest advances. Taking an industrial approach, it explores radiotracer techniques in ADME studies, accelerator mass spectrometry equipment, radioluminography, positron emission tomography, and gamma-scintigraphy. It features examples and illustrations on how collected data is used in drug research. Aimed at researchers in the pharmaceutical, agrochemical, and animal health indus
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Drug development -- Methodology
Radioactive tracers.
Radioactive Tracers
Drug Industry -- methods
Scintillation Counting -- methods
MEDICAL -- Drug Guides.
MEDICAL -- Pharmacology.
MEDICAL -- Pharmacy.
MEDICAL -- Nursing -- Pharmacology.
Radioactive tracers
Form Electronic book
Author Temple, Simon
LC no. 2005030546
ISBN 1420004980