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Title Neuroinflammation and CNS disorders / [edited by] Nicola Woodroofe and Sandra Amor
Published Chichester, West Sussex, UK ; Hoboken, NJ : John Wiley & Sons, 2014


Description 1 online resource
Contents Immune privilege of the brain -- Innate immunity in the CNS : a focus on the myeloid cell -- Adaptive immune responses in the CNS -- Ageing and the immune response in the CNS -- Brain repair : the role of endogenous and transplanted neural stem cells -- Neuroinflammation in Alzheimer's, Parkinson's, and Huntington's diseases -- CNS infections -- Neuroimmunology of amyotrophic lateral sclerosis -- Demyelinating disorders of the CNS -- Other autoimmune disorders : systemic lupus erythematosus, primary Sjogren's syndrome, gluten-related neurological dysfunction, and paraneoplastic neurological syndromes -- Inflammation in the pathogenesis of depression -- Immune responses in the CNS in epilepsy -- Inflammatory mediators and dysfunction of the neurovascular unit following ischaemia reperfusion -- Spinal cord injury -- Immune responses to tumours in the CNS
Summary The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this delicate balance are involved in many disorders. This has opened up n
Bibliography Includes bibliographical references and index
Notes Print version record and CIP data provided by publisher
Subject Nervous system -- Degeneration -- Immunological aspects
Autoimmune diseases.
Central nervous system -- Diseases -- Immunological aspects
Inflammation -- Pathophysiology
Central nervous system -- Immunology.
Neurodegenerative Diseases -- immunology
Autoimmune Diseases
Autoimmune Diseases -- physiopathology
Central Nervous System Diseases -- immunology
Central Nervous System Diseases -- physiopathology
Inflammation -- physiopathology
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Autoimmune diseases
Inflammation -- Pathophysiology
Form Electronic book
Author Woodroofe, Nicola, editor
Amor, Sandra, editor
LC no. 2013051181
ISBN 9781118406540