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Title Array comparative genomic hybridization : protocols and applications / edited by Diponkar Banerjee, Sohrab P. Shah
Published New York : Humana Press : Springer, ©2013


Description 1 online resource (xii, 382 pages) : illustrations (some color)
Series Methods in molecular biology, 1940-6029 ; 973
Methods in molecular biology (Clifton, N.J.) ; v. 973. 0277-786X
Contents Array comparative genomic hybridization : an overview of protocols, applications, and technology trends / Diponkar Banerjee -- Ultradense array CGH and discovery of micro-copy number alterations and gene fusions in the cancer genome / Ewa Przybytkowski [and others] -- Epigenomics : sequencing the methylome / Martin Hirst -- Application of array comparative genomic hybridization in chronic myeloid leukemia / Seonyang Park [and others] -- Use of cytogenetic microarrays in myelodysplastic syndrome Characterization / Lisa G. Shaffer, Blake C. Ballif, and Roger A. Schultz -- CGH protocols : chronic lymphocytic leukemia / Esteban Braggio, Rafael Fonseca, and Neil E. Kay -- Analysis of Acquired genomic copy number aberrations and regions of loss of heterozygosity in acute myelogenous leukemia genomes using affymetrix SNP 6.0 arrays and supporting software tools / Peter D. Ouillette [and others] -- Clinical applications of BAC array-CGH to the study of diffuse large B-cell lymphomas / Cristina Robledo, Juan Luis Garcia, and Jesus M. Hernandez -- Genomic profiling of mantle cell lymphoma / Melissa Rieger Menanteau and Jose A. Martinez-Climent -- Copy number analysis in EBV-positive nodal peripheral T cell lymphoma, unspecified / Kyusam Choi, Hyunjeong Ju, and Young Hyeh Ko -- Mycosis fungoides and Sezary syndrome / Blanca Espinet and Rocio Salgado -- Array CGH reveals clonal evolution of adult T-cell leukemia/lymphoma / Akira Umino and Masao Seto -- Array-CGH analysis of cutaneous anaplastic large cell lymphoma / K. Szuhai [and others] -- Genome-wide DNA profiling of HIV-related B-cell lymphomas / Andrea Rinaldi [and others] -- Array comparative genomic hybridization in osteosarcoma / Bekim Sadikovic [and others] -- Comparative genomic hybridization of Wilms' tumor / Shahrad Rod Rassekh and Evica Rajcan-Separovic -- Array-CGH in childhood MDS / Marcel Tauscher, Inka Praulich, and Doris Steinemann -- Nonfamilial breast cancer subtypes / Markus Ringner, Johan Staaf, and Goran Jonsson -- Applications of array-CGH for lung cancer / Kenneth J. Craddock, Wan L. Lam, and Ming-Sound Tsao -- Array CGH in brain tumors / Gayatry Mohapatra, Julia Sharma, and Stephen Yip -- Finding common regions of alteration in copy number data / Oscar M. Rueda, Ramon Diaz-Uriarte, and Carlos Caldas -- Distinguishing somatic and germline copy number events in cancer patient DNA hybridized to whole-genome SNP genotyping arrays / Gavin Ha and Sohrab Shah
Summary The earliest descriptions of human chromosomes initiated the genomics revolution that is now upon us. Array Comparative Genomic Hybridization: Protocols and Applications explores the scope of what is now possible as far as documenting abnormalities associated with several human cancers. While the technology for interrogating the human genome continues to evolve, refinement of comparative genomic hybridization (CGH) using array CGH and related technologies have provided enormous insight into human cancers at an affordable scale. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Array Comparative Genomic Hybridization: Protocols and Applications provides researchers with well-honed methodologies to learn these techniques for their own use in research or clinical diagnostic laboratories
Analysis geneeskunde
biomedische wetenschappen
humane genetica
human genetics
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Comparative genomic hybridization.
Nucleic acid hybridization.
Nucleic Acid Hybridization
Nucleic acid hybridization
Comparative genomic hybridization
Genre/Form Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Banerjee, Diponkar.
Shah, Sohrab P.
ISBN 9781627032810