| Description |
1 online resource (430 p.) |
| Contents |
Cover -- Title Page -- Copyright Page -- Dedication Page -- Contents -- List of Contributors -- Preface -- Chapter 1 Pharmacokinetics and Pharmacodynamics -- Introduction -- Pharmacokinetics -- Absorption and Bioavailability -- Distribution -- Metabolism (Biotransformation) -- Elimination -- Pharmacokinetic Models -- Pharmacodynamics -- Receptors -- Pharmacokinetic/Pharmacodynamic Modeling -- References -- Further Reading -- Chapter 2 Pharmacogenetics in Veterinary Anesthesia and Analgesia -- Introduction -- Pharmacogenetics -- Historical Perspectives -- Pharmacogenetics -- Current Situation |
|
Pharmacogenetics -- Cytochrome P450 Function -- Genetic Variations in Drug Disposition -- Pharmacogenomics of Drug Metabolism in Veterinary Patients -- Polymorphisms of CYP450 -- Cytochrome P450 1A2 -- Cytochrome P450 2B -- Cytochrome P450 2C -- Cytochrome P450 2D -- Cytochrome P450 2E -- Cytochrome P450 3A -- Other Polymorphisms of Relevance Based upon Clinically Recognized Phenomena -- Drug Transporters -- Feline Hypokalemia -- Inherited Ventricular Arrhythmias and Sudden Death of German Shepherd Dogs -- Opioids and Other Polymorphisms -- References |
|
Respiratory System -- Central Nervous System -- Renal System -- Other Effects -- References -- Chapter 6 Benzodiazepines -- Introduction -- Structures and Mechanisms of Action -- Molecular Structure of Benzodiazepines -- Benzodiazepine Interaction with GABAA Receptors -- Pharmacokinetic Properties -- Routes of Administration -- Protein Binding -- Metabolism -- Excretion -- Indications and Pharmacodynamic Effects -- Hypnotic and Anxiolytic -- Anesthetic Sparing -- Anticonvulsant and Central Nervous System Effects -- Muscle Relaxation -- Amnesic Effects -- Appetite Stimulation -- Side Effects |
| Notes |
Description based upon print version of record |
|
Respiratory and Cardiovascular |
| Genre/Form |
Electronic books
|
| Form |
Electronic book
|
| Author |
Lerche, Phillip
|
| ISBN |
9781118975145 |
|
1118975146 |
|
