Title Tumor-suppressing viruses, genes, and drugs : innovative cancer therapy approaches / edited by Hiroshi Maruta

Published San Diego : Academic Press, ©2002

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Description 1 online resource (xv, 425 pages) : illustrations Contents Ch. 1. Oncolytic viruses: virotherapy for cancer -- Ch. 2. Reovirus therapy of Ras-associated cancers -- Ch. 3. Oncolytic herpes simplex virus (G207) therapy: from basic to clinical -- Ch. 4. p53 and its targets -- Ch. 5. Prospects for tumor suppressor gene therapy: RB as an example -- Ch. 6. CDK inhibitors: genes and drugs -- Ch. 7. CDK inhibitors: small molecular weight compounds -- Ch. 8. NF1 and other RAS-binding peptides -- Ch. 9. Cytoskeletal tumor suppressor genes -- Ch. 10. TGF-[beta] signaling and carcinogenesis -- Ch. 11. DAN gene -- Ch. 12. Design of hammerhead ribozymes and allosterically controllable maxizymes for cancer gene therapy -- Ch. 13. Inhibitors of angiogenesis -- Ch. 14. Geranylgeranylated RhoB mediates the apoptotic and antineoplastic effects of farnesyltransferase inhibitors: new insights into cancer cell suicide -- Ch. 15. RAS binding compounds -- Ch. 16. Actin-binding drugs: MKT-007 and chaetoglobosin K (CK) -- Ch. 17. Tyr kinase inhibitors as potential anticancer agents: EGF receptor and ABL kinases -- Ch. 18. Antagonists of Rho family GTPases: blocking PAKs, ACKs, and rock -- Ch. 19. Integrin antagonists as cancer therapeutics -- Ch. 20. Functional rescue of mutant p53 as a strategy to combat cancer Summary Tumor Suppressing Viruses, Genes, and Drugs profiles the new generation of cancer treatments now in development. The book examines the innovative new approaches of viral, gene, and signal therapies that promise to replace or enhance conventional methods such as surgery, radiation, and chemotherapy. The timely information presented by this book should be of interest to anyone concerned with advancing cancer treatment beyond current medical practices Bibliography Includes bibliographical references and index Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL English Print version record digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL Subject Antioncogenes. Cancer -- Gene therapy. Viruses -- Therapeutic use Cancer -- Treatment -- Technological innovations. Cancer -- Molecular aspects. Gene therapy. Neoplasms -- therapy Antineoplastic Agents -- therapeutic use Genetic Therapy Genes, Tumor Suppressor Neoplasms -- genetics Neoplasms -- virology MEDICAL -- Oncology. HEALTH & FITNESS -- Diseases -- Cancer. Gene therapy Antioncogenes Cancer -- Gene therapy Cancer -- Molecular aspects Cancer -- Treatment -- Technological innovations Viruses -- Therapeutic use Tumeurs -- thérapie. Gentherapie Tumorhemmung Krebs Medizin Pharmakotherapie Cancer -- Chimiothérapie. Cancer -- Thérapie génique. Virus -- Emploi en thérapeutique. Form Electronic book Author Maruta, Hiroshi. ISBN 9780080549026 0080549020 1281119237 9781281119230 9786611119232 661111923X

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