Description |
1 online resource (viii, 383 pages) : illustrations (some color) |
Series |
2012-2013 Springer E-Books - Biomedical & Life Sciences
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Contents |
Histopathology and grading of breast cancer / Magda Esebua -- Multicentric/multifocal breast cancer: overview, biology and therapy / Federico Buggi and Annalisa Curcio -- The immune system in breast cancer initiation and progression: role of epithelial to mesenchymal transition / Keith L. Knutson and Derek C. Radisky -- Remodeling of the extracellular matrix: implications for cancer / Thomas R. Cox and Janine T. Erler -- Biology and treatment of basal-like breast cancer / Bingchen Han, William Audeh and Yanli Jin -- Re-excision after lumpectomy for breast cancer / Suzanne B. Coopey -- Novel anti-angiogenic therapies using naturally-occurring and synthetic drugs to combat progestin-dependent breast cancer / Salman M. Hyder and Benford Mafuvadze -- New insights on estrogen receptor actions in hormone-responsive breast cancer cells by interaction proteomics / Concetta Ambrosino and Roberta Tarallo -- Reprogramming breast cancer cells with embryonic microenvironments: insights from nodal signaling / Gina Kirsammer and Mary J.C. Hendrix -- Metastatic determinants: breast tumour cells in circulation / Nisha Kanwar and Susan J. Done -- Breast cancer epigenetics: biomarkers and therapeutic potential / Nancy H. Nabilsi and Carolina E. Pardo -- The impact of centrosome abnormalities on breast cancer development and progression with a focus on targeting centrosomes for breast cancer therapy / Heide Schatten -- A New Perspective on Cyclin D1: beyond cell cycle regulation / Chenguang Wang and Timothy G. Pestell -- Gene signatures of inflammatory breast cancer: epithelial plasticity and a cancer stem cell phenotype / Fredika M. Robertson and Khoi Chu -- An integrated human mammary epithelial cell culture system for studying carcinogenesis and aging / Martha R. Stampfer and Mark A. LaBarge -- New breast cancer treatment considerations : a brief review of the use of genetically modified (attenuated) bacteria as therapy for advanced and metastatic breast cancer. / Robert A. Kazmierczak and Alison Dino |
Summary |
Highlighting recent advances in our understanding of breast cancer, this book is intended for a wide audience as a reference book. Included are reviews of genetics, epigenetics, various aspects of cell and molecular biology, and several other areas of breast cancer that are aimed at determining new intervention sites for treatments and cures of the disease. The chapters are written by internationally recognized experts and include reviews of key topics in breast cancer research. Each chapter highlights the new aspects of specific research topics, the various impacts of designing new strategies, and identifies new targets for therapeutic intervention. The topics addressed are selected to be of interest to patients, scientists, students, teachers, and to all who are interested in expanding their knowledge of breast cancer imaging, diagnostics, therapeutics, or basic biomedical research on breast cancer |
Notes |
Includes index |
Bibliography |
ReferencesChapter 3: The Immune System in Breast Cancer Initiation and Progression: Role of Epithelial to Mesenchymal Transition; 3.1 Introduction; 3.2 Inflammation in Initiation and Progression of Breast Cancer; 3.2.1 As a Mucosal Tissue, the Mammary Gland and the Immune System Are Naturally Linked; 3.2.2 Is Chronic Inflammation Linked to Breast Cancer Incidence or Disease Progression?; 3.3 The Tumor Immune Microenvironment; 3.3.1 The Role of Infiltrating Immune Effectors in Disease Pathogenesis and Survival; 3.3.2 Epithelial to Mesenchymal Transition |
Notes |
English |
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Online resource; title from PDF title page (SpringerLink, viewed October 15, 2013) |
In |
Springer eBooks |
Subject |
Breast -- Cancer -- Molecular aspects
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Microscopy.
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Breast Neoplasms
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Microscopy
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microscopy.
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HEALTH & FITNESS -- Diseases -- General.
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MEDICAL -- Clinical Medicine.
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MEDICAL -- Diseases.
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MEDICAL -- Evidence-Based Medicine.
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MEDICAL -- Internal Medicine.
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Breast -- Cancer -- Molecular aspects
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Form |
Electronic book
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Author |
Schatten, Heide, editor
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ISBN |
9781627036344 |
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1627036342 |
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1627036334 |
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9781627036337 |
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