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Book Cover
E-book
Author Vardanyan, R. S. (Ruben S.)

Title Synthesis of essential drugs / R.S. Vardanyan, V.J. Hruby
Edition 1st ed
Published Amsterdam ; Boston : Elsevier, 2006

Copies

Description 1 online resource (xvi, 617 pages) : illustrations
Contents 1. General Anesthetics -- -- 2. Local Anesthetics -- -- 3. Analgesics -- -- 4. Hypnotics and Sedatives -- -- 5. Anxiolitics (Tranquilizers) -- -- 6. Antipsycotics (Neuroleptics) -- -- 7. Antidepressants -- -- 8. Central Nervous System Stimulants -- -- 9. Antiepileptics -- -- 10. Anti-Parkinson Drugs -- -- 11. Adrenegic (Sympatomimetic) Drugs -- -- 12. Adrenoblocking Drugs -- -- 13. Cholinomimetics -- -- 14. Anticholinergic Drugs -- -- 15. Muscle Relaxants -- -- 16. Antihistamine Drugs -- -- 17. Cardiac Glycosides and Other Inotropes -- -- 18. Drugs for Tachyarrhytmias -- -- 19. Antianginal Drugs -- -- 20. Agents Used in Hyperlipoproteinemia -- -- 21. Diuretics -- -- 22. Antihypertensive Drugs -- -- 23. Drugs for Treating of Pulmonary Diseases -- -- 24. Anticoagulants, Antiagregants, Trombolytics and Hemostatics -- -- 25. Thyroid and Parathyroid Drugs -- -- 26. Insulin and Synthetic Hypoglycemic Agents -- -- 27. Corticosteroids -- -- 28. Female Sex Hormones -- -- 29. Male Sex Hormones and Anabolics -- -- 30. Antineoplastic Agents -- -- 31. Immunopharmacologic Drugs -- -- 32. Antibiotics -- -- 33. Antimicrobials -- -- 34. Antimicobacterials -- -- 35. Antifungal Drugs -- -- 36. Antiviral Drugs -- -- 37. Antiprotozoal Drugs -- -- 38. Antihelmint Drugs
Summary This book represents an effort to express a long overdue need of compiling information which has been accumulated over the course of more than 30 years of our work in the area of the synthesis of medicinal drugs. Our effort fills obvious gaps that exist in the literature of drug synthesis. The synthesis of various groups of drugs are presented in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed description of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, we mainly discuss generic drugs that are included in the WHOs "Essential List of Drugs." For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. This book will provide the kind of information that will be of interest to those who work, or plan to begin work in the captivating areas of biologically active compounds and the synthesis of medicinal drugs. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Pharmaceutical chemistry.
Drugs -- Design.
Chemical models.
Drugs, Essential -- chemical synthesis
Chemistry, Pharmaceutical
Chemistry, Pharmaceutical -- methods
Drug Design
Models, Chemical
MEDICAL -- Drug Guides.
MEDICAL -- Pharmacology.
MEDICAL -- Pharmacy.
MEDICAL -- Nursing -- Pharmacology.
Chemical models
Drugs -- Design
Pharmaceutical chemistry
Form Electronic book
Author Hruby, Victor J., 1938-
ISBN 9780444521668
0444521666
008046212X
9780080462127