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Title Recombinant virus vaccines : methods and protocols / edited by Maureen C. Ferran and Gary R. Skuse
Published New York : Humana Press : Springer, [2017]
©2017

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Description 1 online resource (x, 273 pages) : illustrations (chiefly color)
Series Methods in molecular biology ; 1581
Methods in molecular biology (Clifton, N.J.) ; v. 1581. 1064-3745
Contents Development of novel vaccines against infectious diseases based on chimpanzee adenoviral vector / Chao Zhang, Yudan Chi, and Dongming Zhou -- Development of recombinant canarypox viruses expressing immunogens / Débora Garanzini, María Paula Del Médico-Zajac, and Gabriela Calamante -- Fowl adenovirus-based vaccine platform / Juan C. Corredor, Yanlong Pei, and Éva Nagy -- Development of recombinant HSV-based vaccine vectors / Richard Voellmy, David C. Bloom, Nuria Vilaboa, and Joyce Feller -- Generating recombinant pseudorabies virus for use as a vaccine platform / Feifei Tan, Xiangdong Li, and Kegong Tian -- Generation and production of modified vaccinia virus ankara (MVA) as a vaccine vector / Vincent Pavot, Sarah Sebastian, Alison V. Turner, Jake Matthews, and Sarah C. Gilbert -- Poxvirus safety analysis in the pregnant mouse model, vaccinia, and raccoonpox viruses / Rachel L. Roper -- Development of recombinant arenavirus-based vaccines / Luis Martínez-Sobrido and Juan Carlos de la Torre -- Development of recombinant measles virus-based vaccines / Michael D. Mühlebach and Stefan Hutzler -- Recombinant tri-segmented pichinde virus as a novel live viral vaccine platform / Rekha Dhanwani, Hinh Ly, and Yuying Liang -- Human rhinovirus-A1 as an expression vector / Khamis Tomusange, Danushka Wijesundara, Eric James Gowans, and Branka Grubor-Bauk -- Generating recombinant vesicular stomatitis viruses for use as vaccine platforms / John B. Ruedas and John H. Connor -- Alphavirus-based vaccines / Kenneth Lundstrom -- Display of HIV-1 envelope protein on lambda phage scaffold as a vaccine platform / Jonelle L. Mattiacio, Matt Brewer, and Stephen Dewhurst -- Bacteriophage T4 as a nanoparticle platform to display and deliver pathogen antigens : construction of an effective anthrax vaccine / Pan Tao, Qin Li, Sathish B. Shivachandra, and Venigalla B. Rao
Summary This volume provides readers with methods and protocols for understanding the development of recombinant viruses and their use as vaccines platforms. Recombinant Virus Vaccines: Methods and Protocols details the use of recombinant vaccines that are employed to either produce immunogens in vitro or elicit antibody production in vivo. The chapters in this book are divided into four parts: Part I explores double-stranded DNA viruses; Part II discusses negative sense single-stranded RNA viruses; Part III talks about positive sense single-stranded RNA viruses; and Part IV describes bacteriophages. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Recombinant Virus Vaccines: Methods and Protocols is a valuable resource for scientists and clinicians who are interested in learning about and adopting methods for use in basic and biomedical research directed toward generating and developing recombinant viral vaccines
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerProtocols, viewed April 5, 2017)
Subject Viral vaccines.
Synthetic vaccines.
Genetic recombination.
Viral Vaccines
Recombination, Genetic
Vaccines, Synthetic
Immunology.
Medical -- Immunology.
Genetic recombination
Synthetic vaccines
Viral vaccines
Genre/Form Laboratory manuals
Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Ferran, Maureen C., editor.
Skuse, Gary R., editor.
ISBN 9781493968695
1493968696