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E-book

Title Translational nanomedicine / edited by Robert A. Meyers
Published Weinheim, Germany : Wiley-VCH Verlag GmbH & Co. KGaA, [2020]

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Description 1 online resource (ix, 473 pages) : color illustrations
Series Advances in molecular biology and medicine
Advances in molecular biology and medicine.
Contents Part I Laboratory Techniques -- Chapter 1 Microfluidics in Nanomedicine -- 1 Introduction -- 1.1 Nanomedicine Development -- 1.2 Microfluidics Technology -- 2 Microfluidic Assembly of Nanomedicines -- 3 Microfluidic Characterization of Nanomedicines -- 4 Microfluidic Evaluation of Nanomedicines -- 4.1 Mimicking Physiological Environments -- 4.2 Endothelial Cell Systems -- 4.3 "Organ-On-A-Chip" -- 4.4 Renal Toxicity and Hepatotoxicity -- 4.5 Live Tissue Explants -- 5 Challenges and Opportunities -- 6 Concluding Remarks
Acknowledgments -- References -- Chapter 2 Quantum Dots for Biomedical Delivery Applications -- 1 Introduction -- 2 Properties of QDs -- 3 Lithographically Defined QDs -- 4 Colloidal QDs -- 5 QDs Application in Optics -- 6 Transport (Electrical) Properties of QDs -- 7 Application of QDs in Diagnostics -- 8 Nucleic Acid Detection -- 9 Application of QDs in Drug Treatments -- Acknowledgments -- References -- Part II Devices -- Chapter 3 DNA Origami Nanorobots -- 1 Introduction to Robotics -- 1.1 A Brief History of Robotics -- 1.2 Robotic Control of Molecules -- 2 DNA Nanotechnology -- 2.1 Computing
2.2 Nanofabrication -- 2.3 Nucleic Acid Enzymes -- 2.4 Nucleic Acid Sensors -- 2.5 DNA Actuators and Motors -- 2.6 Miscellaneous Functions of Nucleic Acids -- 2.7 DNA Origami -- 2.8 Computer-Aided Design (CAD) Tools for DNA Nanostructures -- 2.9 Designing Scaffolded Origami in caDNAno: A Guided Tour -- 3 DNA Nanorobotics -- 3.1 Case Study: A DNA Nanorobot -- 3.2 Sensing the Environment -- 3.3 Information Processing and Logic Types -- 3.4 Collective Behaviors -- 3.5 Synthetic Genetic Circuits and DNA Nanorobotics -- 4 Challenges of Applying DNA Nanorobots to Therapeutics
5 Summary and Conclusions -- References -- Chapter 4 Graphene and Graphene Derivatives in Biosensing, Imaging, Therapeutics, and Genetic Engineering -- 1 Introduction -- 2 Biosensing -- 2.1 Modification of Bioreceptor on Graphene by Covalent and Noncovalent Interactions -- 2.2 Advantage of Graphene/Nanoparticle Hybrids in Enhancing Transducer Performance -- 3 Bioimaging -- 3.1 Optical Imaging: NIR Imaging, Fluorescence, Multiphoton Excitation Imaging -- 3.1.1 NIR Imaging -- 3.1.2 Fluorescence Imaging -- 3.1.3 Multiphoton Excitation Imaging -- 3.2 Localized Surface Plasmon Resonance (LSPR)
3.3 Raman Imaging -- 3.4 Magnetic Resonance Imaging (MRI) -- 3.5 Positron Emission Tomography (PET) -- 4 Therapeutics -- 4.1 Drug Loading by Noncovalent Interactions -- 4.2 Drug Loading by Host-Guest Interaction -- 4.3 Controlled Release System -- 4.4 Photodynamic and Photothermal Therapy -- 4.5 Combination of Diagnostics and Therapeutics: Graphene-Based Theranostics System -- 5 Genetic Engineering -- 6 Conclusions -- Acknowledgments -- References -- Chapter 5 Synthetic Gene Circuits -- 1 Introduction to Synthetic Gene Circuits -- 2 Building Blocks of Synthetic Gene Circuits
Summary "The largest high-level encyclopedia on molecular medicine is now publishing a topical volume on Nanomedicine. The long awaited volume gives a comprehensive overview on nanomaterials in drug delivery, imaging and as therapeutics."-- Provided by publisher
Bibliography Includes bibliographical references and index
Notes 2.1 The Chassis: Choice of the Host Cell
Online resource; title from PDF title page (EBSCO, viewed October 28, 2020)
Subject Nanomedicine.
Nanomedicine
Nanomedicine
Form Electronic book
Author Meyers, Robert A. (Robert Allen), 1936- editor.
ISBN 352768431X
9783527684311
9783527337897 (hbk.)
352733789X (hbk.)