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Book Cover
E-book
Author Mtewa, Andrew G

Title Poisonous Plants and Phytochemicals in Drug Discovery
Published Newark : John Wiley & Sons, Incorporated, 2020

Copies

Description 1 online resource (426 p.)
Contents Cover -- Title Page -- Copyright Page -- Contents -- List of Contributors -- List of Figures -- Listof Tables -- Preface -- Editors -- Chapter 1 Historical Use of Toxic Plants -- 1.1 Introduction to Toxic Plants -- 1.2 Poisonous Plants as Sources of Traditional and Modern Medicines -- 1.3 Toxic Plants and Justice -- 1.3.1 Toxic Plants in Capital Punishment -- 1.3.2 Trial by Ordeal -- 1.4 Toxic Plants in Poisoned Weapons -- 1.4.1 Arrow Poisons -- 1.5 Plant Fishing Poisons/Piscicides/Ichthyotoxins -- 1.6 Poisonous Plants as Food -- 1.7 Poisonous Plants as Biopesticides
1.8 Toxic Psychoactive Plants for Recreational and Religious Purposes -- 1.9 Poisonous Plants in Warfare and Bioterrorism -- 1.10 Poisonous Plants as Carcinogens and Teratogens -- 1.11 Conclusion -- References -- Chapter 2 Classification of Phytotoxins and their Mechanisms of Action -- 2.1 Introduction -- 2.1.1 Endophytic Phytotoxins -- 2.1.2 Secondary Metabolites -- 2.2 Possible Categorization -- 2.2.1 Biological Characteristics -- 2.2.2 Chemical Characteristics -- 2.3 Currently Available Classification Tools -- 2.4 Role of Phytotoxin Classification -- 2.4.1 Drug Discovery
2.4.2 Environmental Monitoring -- 2.4.3 Phytotoxins, Aquatic Life, and Water Quality -- 2.4.4 Air Contamination -- 2.4.5 Food Contamination -- 2.4.6 Security and Safety Services -- 2.4.7 Agricultural -- 2.5 Brief Mechanisms of Action -- 2.6 Conclusion -- References -- Chapter 3 Poisonous Plants as Sources of Anticancer and Other Drugs -- 3.1 Introduction -- 3.2 Poisonous Plants in the Treatment of Cancer and Other Diseases -- 3.3 Poisonous Plant-Based Anticancer Drugs that are on the Market -- 3.4 Poisonous Plant-Based Drugs Against Other Diseases that are on the Market -- 3.5 Conclusion
4.2.6.2 Colchicine -- 4.2.6.3 Coumarins -- 4.2.6.4 Nicotine and the Neonicotinoids -- References -- Chapter 5 Toxicology and Health Benefits of Plant Alkaloids -- 5.1 Introduction -- 5.2 Pharmacological Properties of Alkaloids -- 5.3 Toxicological Properties of Alkaloids -- 5.4 Acute and Chronic Toxicities -- 5.4.1 Genotoxicity and Tumorigenicity -- 5.4.2 Lung Toxicity, Neurotoxicity, and Teratogenicity -- 5.5 Factors that Influence the Toxicological Profile of Alkaloids -- 5.6 Conclusion -- References -- Chapter 6 Chemical and Pharmacological Mechanisms of Plant-Derived Neurotoxins
Notes Description based upon print version of record
Bibliography References -- Chapter 4 Drugs in Clinical Practice from Toxic Plants and Phytochemicals -- 4.1 Introduction -- 4.2 Drugs in Clinical Practice from Toxic Plants -- 4.2.1 Curare -- 4.2.2 Drugs Acting on the Central Nervous System -- 4.2.2.1 Morphine -- 4.2.2.2 Cocaine -- 4.2.2.3 Ergot Alkaloids -- 4.2.3 Atropine, Scopolamine, and Hyoscyamine -- 4.2.4 Physostigmine and Other Acetylcholinesterase Inhibitors -- 4.2.5 Antitumor Agents -- 4.2.5.1 Podophyllotoxin and Etoposide -- 4.2.5.2 Taxanes -- 4.2.5.3 Vincristine and Vinblastine -- 4.2.6 Other Drugs -- 4.2.6.1 Cardiac Glycosides
Notes 6.1 Introduction
Subject Botanical chemistry.
Poisonous plants -- Toxicology.
Botanical chemistry
Poisonous plants -- Toxicology
Form Electronic book
Author Egbuna, Chukwuebuka
Rao, G. M. Narasimha
ISBN 9781119650270
1119650275