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Book Cover
E-book
Author Paley, Elena L., author.

Title Microbial metabolism and disease / Elena L. Paley
Published London : Academic Press, [2021]

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Description 1 online resource
Contents Front Cover -- Microbial Metabolism and Disease -- Microbial Metabolism and Disease -- Copyright -- Contents -- 1 -- Naturally occurring affectors of tRNA aminoacylation in transition from health to disease: interference in the ... -- 1.1 Introduction -- 1.2 Experimental evidences supporting the concept -- 1.2.1 Tryptamine-induced neurodegeneration in cell and animal models -- 1.2.2 Alzheimer disease is a systemic widespread disease -- 1.2.3 Seizures and myoclonus in Alzheimer disease and in tryptamine-treated animals -- 1.2.4 Serotonin (5-HT) or tryptamine syndrome
1.2.5 Metabolic syndrome -- 1.2.6 Tryptamine, biogenic amines, and polyamines affect tRNA aminoacylation and protein biosynthesis -- 1.2.7 Protein biosynthesis in Alzheimer disease and in cancer -- 1.2.8 Mutations of genes encoding cytoplasmic (WARS) and mitochondrial (WARS2) TrpRS leading to TrpRS deficiency, Parkinsonism, a ... -- 1.2.9 The accumulation of defective proteins induces antigenicity -- 1.3 Conclusions -- 2 -- Physicochemical, biochemical, and cell biology properties and byproducts of tryptamine and other "trace" amines
3 -- Tryptophan metabolites and biogenic amines in physical exercises and metabolic syndrome -- 4 -- Tryptamine in inflammation and regulation of gene transcription -- 5 -- Genes encoding mammalian, plant, and microbial aromatic amino acid decarboxylase -- 5.1 Mammalian aromatic acid decarboxylase -- 5.2 Bacterial aromatic l-amino acid decarboxylases -- 5.3 Fungal pyridoxal-dependent aromatic-l-amino-acid decarboxylase -- 5.4 Plant tryptophan decarboxylase -- 5.5 Conclusion -- 6 -- Decarboxylases producing tryptamine and other biogenic amines in the human microbiome -- 6.1 Conclusion
7 -- Microbial shikimate pathway in diseases -- 7.1 Apicomplexan parasites -- 7.2 Effect of tryptamine and other tryptophan-related compounds on shikimate pathway enzymes -- 7.3 Pyridoxal phosphate-dependent enzymes -- 7.4 Metabolic engineering -- 7.5 Inhibitors of shikimate pathway enzymes -- 7.6 Conclusion -- 8 -- Biogenic amines in fasting, feeding, and stress conditions -- 8.1 Fasting, starvation, and feeding -- 8.2 Anorectic effect -- 8.3 Stress factors -- 8.4 Stress and mucus -- 8.5 Irritable bowel syndrome: poor sleep -- 8.6 Conclusions
9 -- Metabolites of shikimate and tryptophan pathways in coronavirus disease (COVID-19) -- 9.1 Comparison of statistics for age-related diseases COVID-19 and Alzheimer disease -- 9.2 Proteomic and metabolomic profiling of sera from COVID-19 patients and further discussion -- 9.3 Postmortem studies of COVID-19 patients in different countries -- 9.4 Conclusions -- 10 -- Virulence factors -- 10.1 Bacteria and virus interactions in influenza -- 10.2 Decarboxylase and viral infection
Bibliography Includes bibliographical references and index
Subject Microbial metabolism.
Microbial metabolism
Form Electronic book
ISBN 9780323884464
0323884466