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Book Cover
E-book

Title The Ras superfamily of GTPases / [edited by] Juan Carlos Lacal, Frank McCormick
Published Boca Raton, FL : CRC Press, 2018
©1993

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Description 1 online resource (526 pages, 3 unnumbered pages of plates) : illustrations (some color)
Series CRC revivals
CRC revivals.
Contents Cover; Half Title; Title Page; Copyright Page; PREFACE; TABLE OF CONTENTS; I: THE WORLD OF ras GENES AND THEIR PRODUCTS; Oncogenic Potential of ras Genes; Chapter 1 ras Genes Involvement in Carcinogenesis: Lessons from Animal Model Systems; Structure and Properties of ras Proteins; Chapter 2 Three-Dimensional Structure of p2l and Its Implications; Chapter 3 Posttranslational Processing of ras and ms-Related Proteins; Chapter 4 Biological Activities of ras Genes; Chapter 5 p2l-ras and Receptor Signaling; Chapter 6 ras-p21 Proteins: Switch Devices for Signal Transduction
Genetic Approaches to ras FunctionChapter 7 The RAS System in Yeasts; Chapter 8 Regulation and Function of Two Developmentally Regulated ras Genes in Dictyostelium; Chapter 9 ras Genes in Drosophila melanogaster; II: THE ras SUPERFAM; General Overview; Chapter 10 ras Homologs: A Comparison of Primary Structures; The ras Branch; Chapter 11 Krev-1 and the Related Genes; Chapter 12 ral Gene Products and Their Regulation; The rho Branch; Chapter 13 The rho Gene Family; Chapter 14 rac Gene Products
Chapter 15 CDC42: A Member of the ras Superfamily Involved in the Control of Cellular Polarity during the Saccharomyces cerevisiae Cell CycleChapter 16 CDC42Hs: The Human Homolog of a Yeast Cell-Division Cycle Protein; Chapter 17 Identification of Novel ras Family Genes in a Human Teratocarcinoma Cell Line by Oligonucleotide Screening; The rab Branch; Chapter 18 The rab Gene Family; Chapter 19 The YPT Protein Family in Yeast; Chapter 20 The SAS Genes: Functionally Distinct Members of the YPT1/SEC4 Family in Dictyostelium; III: FUNCTIONAL REGULATION OF ras AND ras-RELATED GTPases
GAPs and Related FactorsChapter 21 Regulators and Effectors of ras Proteins; Chapter 22 Properties of GAP Proteins; Chapter 23 The IRA Gene Family in Yeast; Chapter 24 GAPs Specific for the rapl/Krev-1 Protein; Exchange Factors for ras and ras-Related Proteins; Chapter 25 Exchange Factors; Chapter 26 Properties of CDC25-Like Proteins; Chapter 27 GDP/GTP Exchange Proteins for Small GTP-Binding Proteins; Index
Summary "The ras Superfamily of GTPases presents the most comprehensive compilation of information available regarding aspects of the putative function of small ras-related GTPases. The book's chapters were written by the world's most prominent scientists in this field and cover such topics as the structure and properties of ras proteins, ras function, the ras superfamily in general, and the functional regulation of ras and ras-related GTPases. The book will benefit cell biologists, oncologists, neurobiologists, molecular biologists, and others interested in the topic."--Provided by publisher
Bibliography Includes bibliographical references and index
Notes Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL
Subject Ras oncogenes.
Guanosine triphosphatase.
Guanosine triphosphatase genes.
Ras proteins.
GTPase-activating protein.
Cell transformation.
Genes, ras
GTP Phosphohydrolases
ras Proteins
GTPase-Activating Proteins
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
SCIENCE -- Life Sciences -- Cytology.
SCIENCE -- Life Sciences -- Biology -- Molecular Biology.
MEDICAL -- Oncology.
Cell transformation
GTPase-activating protein
Guanosine triphosphatase
Guanosine triphosphatase genes
Ras oncogenes
Ras proteins
Form Electronic book
Author Lacal, Juan Carlos, editor.
McCormick, Frank, 1950- editor.
ISBN 9780203709931
0203709934
9781351356855
1351356852
9781351356848
1351356844
9781351356831
1351356836