Title Computational methods in synthetic biology / edited by Mario Andrea Marchisio

Published New York : Humana Press, [2015] ©2015

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Description 1 online resource (xi, 358 pages) : illustrations (some color) Series Methods in molecular biology, 1940-6029 ; 1244 Methods in molecular biology (Clifton, N.J.) ; v. 1244. 1064-3745 Contents Computational protein design methods for synthetic biology -- Computer-aided design of DNA origami structures -- Computational design of RNA parts, devices, and transcripts with kinetic folding algorithms implemented on multiprocessor clusters -- Regulatory RNA design through evolutionary computation and strand displacement -- Programming languages for circuit design -- Kappa rule-based modeling in synthetic biology -- Modular design of synthetic gene circuits with biological parts and pools -- Computationally guided design of robust gene circuits -- Chemical master equation closure for computer-aided synthetic biology -- Feedback loops in biological networks -- Efficient analysis methods in synthetic biology -- Using computational modeling and experimental synthetic perturbations to probe biological circuits -- In silico control of biomolecular processes -- Stochastic modular analysis for gene circuits: Interplay among retroactivity, nonlinearity, and stochasticity -- Distributed model construction with virtual parts -- The synthetic biology open language -- Computational methods for the construction, editing, and error correction of DNA molecules and their libraries Summary This volume provides complete coverage of the computational approaches currently used in Synthetic Biology. Chapters focus on computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Computational Methods in Synthetic Biology serves as a guide to plan in silico the in vivo or in vitro construction of a variety of synthetic bio-circuits Analysis levenswetenschappen life sciences bioinformatics Biology (General) Biologie (algemeen) Bibliography Includes bibliographical references and index Notes English Online resource; title from PDF title page (SpringerLink, viewed December 29, 2014) Subject Synthetic biology -- Laboratory manuals Life sciences. Biology. Computational biology. Bioinformatics. Computer simulation. Digital computer simulation. Engineering. Biological models. Mathematical models. Physical sciences. Synthetic biology. Analytical, Diagnostic and Therapeutic Techniques and Equipment Bioengineering Biological Science Disciplines Biology Computational Biology Computer Simulation Computing Methodologies Disciplines and Occupations Engineering Information Science Investigative Techniques Laboratory Manuals Models, Biological Models, Theoretical Natural Science Disciplines Publication Characteristics Publication Formats Synthetic Biology Technology, Industry, Agriculture Technology, Industry, and Agriculture biological sciences. biology. simulation. engineering. mathematical models. physical sciences. Molecular biology. Science -- Life Sciences -- Anatomy & Physiology. Physical sciences Mathematical models Life sciences Engineering Digital computer simulation Computer simulation Computational biology Biology Biological models Bioinformatics Synthetic biology Genre/Form Laboratory manuals Laboratory manuals. Manuels de laboratoire. Form Electronic book Author Marchisio, Mario Andrea, editor ISBN 9781493918782 1493918788

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