| Description |
1 online resource (xiii, 533 pages) |
| Contents |
Introducing Computational Systems Biology / Roland Eils and Andres Kriete -- Structural Systems Biology: Modeling Interactions and Networks for Systems Studies / Robert B. Russell [and others] -- Understanding Principles of the Dynamic Biochemical Networks of Life Through Systems Biology / Hans V. Westerhoff [and others] -- Biological Foundations of Signal Transduction, Systems Biology and Aberrations in Disease / Ursula Klingmüller [and others] -- Complexities in Quantitative Systems Analysis of Signaling Networks / Christina Kiel and Luis Serrano -- Gene Networks: Estimation, Modeling, and Simulation / Seiya Imoto, Hiroshi Matsuno and Satoru Miyano -- Reconstruction of Metabolic Network from Genome Information and its Structural and Functional Analysis / Hong-Wu Ma and An-Ping Zeng -- Standards, Platforms, and Applications / Stanley Gu and Herbert Sauro -- Databases, Standards, and Modeling Platforms for Systems Biology / Juergen Eilsa [and others] -- Computational Models for Circadian Rhythms: Deterministic versus Stochastic Approaches / Jean-Christophe Leloup, Didier Gonze and Albert Goldbeter -- Top-Down Dynamical Modeling of Molecular Regulatory Networks / Reinhard Laubenbacher and Pedro Mendes -- Discrete Gene Network Models for Understanding Multicellularity and Cell Reprogramming: From Network Structure to Attractor Landscapes Landscape / Joseph Xu Zhou [and others] -- Stochastic Simulations of Cellular Processes: From Single Cells to Colonies / John Cole [and others] -- Advances in Machine Learning for Processing and Comparison of Metagenomic Data / Jean-Luc Bouchot [and others] -- Systems Biology of Infectious Diseases and Vaccines / Helder I Nakaya -- Computational Modeling and Simulation of Animal Early Embryogenesis with the MecaGen Platform / Julien Delile, René Doursat and Nadine Peyriéras -- Developing a Systems Biology of Aging / Andres Kriete and Mathieu Cloutier -- Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme / Hang Chang [and others] -- Applications in Cancer Research: Mathematical Models of Apoptosis / Stefan M. Kallenberger, Stefan Legewie and Roland Eils |
| Summary |
This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. Logical information flow aids understanding of basic building blocks of life through disease phenotypes |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
English |
|
Print version record |
| Subject |
Biological systems -- Computer simulation
|
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Systems biology.
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Computational Biology
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Systems Biology
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NATURE -- Reference.
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SCIENCE -- Life Sciences -- Biology.
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SCIENCE -- Life Sciences -- General.
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Biological systems -- Computer simulation
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Systems biology
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Systembiologie
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Bioinformatik
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| Form |
Electronic book
|
| Author |
Kriete, Andres.
|
|
Eils, Roland.
|
| ISBN |
9780124059382 |
|
0124059384 |
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9781306183932 |
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1306183936 |
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0124059260 |
|
9780124059269 |
|
