Title Tiling arrays : methods and protocols / edited by Tin-Lap Lee, Alfred Chun Shui Luk

Published [Totowa, N.J.] : Humana Press, [2013] ©2013

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Description 1 online resource (xi, 236 pages) : illustrations (some color) Series Methods in molecular biology, methods and protocols, 1940-6029 ; 1067 Methods in molecular biology (Clifton, N.J.) ; v. 1067. 1064-3745 Contents A Brief Introduction to Tiling Microarrays: Principles, Concepts, and Applications -- Design of Tiling Arrays and their Application to Bacterial Transcriptome Analysis -- Transcript Profiling in Arabidopsis with Genome Tiling Microarrays -- Genome-wide Analysis of Transcription Factor Binding Sites in Skeletal Muscle Cells using ChIP-seq -- Analysis of Allele-Specific Gene Expression Using a Target-Oriented Tiling Microarray Assay -- Detection of Epigenetic Alterations Using Tiling Arrays -- Investigating Gene Promoter Methylation in a Mouse Model of Status Epilepticus -- Integrative Analysis of ChIP-chip and ChIP-seq Dataset -- HAT: A Novel Statistical Approach to Discover Functional Regions in the Genome -- Inference of Alternative Splicing from Tiling Array Data -- Analysis of in vivo Occupancy of Aebp1, a Transcription Factor, using High Resolution Tiling Array -- Application of the Simple and Efficient MPeak Modeling in Binding Peak Identification in CHIP-CHIP Studies -- Evaluation of MeDIP-chip in the Context of Whole Genome Bisulphite Sequencing (WGBS-seq) in Arabidopsis -- Mapping Genomic Features of Tiling Microarray Data by TileMapper Summary In Tiling Arrays: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study tiling microarrays in genomic discovery. These include methods and applications for transcriptional regulation, expression, genetic and epigenetic regulation, as well as techniques and skills on tiling microarray data analysis Bibliography Includes bibliographical references and index Notes English Subject DNA microarrays. Nucleic acid hybridization. Genetics -- Technique. Molecular Probe Techniques Microarray Analysis Sequence Analysis Nucleic Acid Hybridization Genetic Techniques Microchip Analytical Procedures Investigative Techniques Analytical, Diagnostic and Therapeutic Techniques and Equipment Chemistry Techniques, Analytical Oligonucleotide Array Sequence Analysis Nucleic acid hybridization Genetics -- Technique DNA microarrays Genre/Form Laboratory manuals. Manuels de laboratoire. Form Electronic book Author Lee, Tin-Lap, editor Shui Luk, Alfred Chun, editor ISBN 9781627036078 1627036075 1627036067 9781627036061

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