Limit search to available items
Did you mean Genes mc? more »
17 results found. Sorted by relevance | date | title .
Book Cover
E-book

Title Oncogenes meet metabolism : from deregulated genes to a broader understanding of tumour physiology / G. Kroemer [and others], editors
Published Berlin ; New York : Springer, ©2008

Copies

Description 1 online resource (xv, 264 pages) : illustrations
Series Ernst Schering Foundation symposium proceedings, 0947-6075 ; 2007-4
Ernst Schering Foundation symposium proceedings ; 2007/4.
Contents Mitochondria and Cancer; Role of the Metabolic Stress Responses of Apoptosis and Autophagy in Tumor Suppression; The Interplay Between MYC and HIF in the Warburg Effect; Using Metabolomics to Monitor Anticancer Drugs; Biomarker Discovery for Drug Development and Translational Medicine Using Metabonomics; Pyruvate Kinase Type M2: A Key Regulator Within the Tumour Metabolome and a Tool for Metabolic Profiling of Tumours; Molecular Imaging of Tumor Metabolism and Apoptosis; Minimally Invasive Biomarkers for Therapy Monitoring; Use of Metabolic Pathway Flux Information in Anticancer Drug Design
Summary In 1920s, Otto Warburg described the phenomenon of a aerobic glycolysisa (TM), the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburga (TM)s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effe
Bibliography Includes bibliographical references
Subject Oncogenes.
Cancer -- Pathophysiology.
Cell metabolism.
Oncogenes
Neoplasms -- genetics
Neoplasms -- metabolism
HEALTH & FITNESS -- Diseases -- Cancer.
Cancer -- Pathophysiology
Cell metabolism
Oncogenes
Genre/Form Electronic books
Form Electronic book
Author Kroemer, Guido.
ISBN 9783540794776
3540794778
9783540794783
3540794786